PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade

A Wiehe, MO Senge - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

Enhanced efficacy and drug delivery with lipid coated mesoporous silica nanoparticles in cancer therapy

MU Amin, S Ali, MY Ali, I Tariq, U Nasrullah… - European Journal of …, 2021 - Elsevier
The exposure of cancer cells to subtherapeutic drug concentrations results in multidrug
resistance (MDR). The uniqueness of mesoporous silica nanoparticles (MSNPs) with larger …

Ultrasound-responsive smart drug delivery system of lipid coated mesoporous silica nanoparticles

MU Amin, S Ali, I Tariq, MY Ali, SR Pinnapreddy… - Pharmaceutics, 2021 - mdpi.com
The immediate release of chemotherapeutics at the target site, along with no premature
release in circulation is always challenging. The purpose of this study was to develop a …

Phototheranostics: An advanced approach for precise diagnosis and treatment of gynecological inflammation and tumors

Q Ding, A Guo, S Zhang, C Gu, X Wang, X Li, M Gu… - Biomaterials, 2024 - Elsevier
Gynecological inflammations have a significant impact on the daily lives of women.
Meanwhile, cancers such as ovarian, cervical, and endometrial cancers pose severe threats …

Recent advances in polymeric core–shell nanocarriers for targeted delivery of chemotherapeutic drugs

X Yang, Y Xie - International Journal of Pharmaceutics, 2021 - Elsevier
The treatment effect of chemotherapeutics is often impeded by nonspecific biodistribution
and limited biocompatibility. Polymeric core–shell nanocarriers (PCS NCs) composed of a …

Promises of phytochemical based nano drug delivery systems in the management of cancer

P Kumar, N Yadav, B Chaudhary, V Jain… - Chemico-Biological …, 2022 - Elsevier
Cancer is the leading cause of human disease and death worldwide, accounting for 7.6
million deaths per year and projected to reach 13.1 million by 2030. Many phytochemicals …

Self-assembled lipid polymer hybrid nanoparticles using combinational drugs for migraine via intranasal route

P Dali, P Shende - AAPS PharmSciTech, 2022 - Springer
The objective of the current research study was to formulate the PEGylated lipid polymer
hybrid nanoparticles of ergotamine and caffeine for intranasal administration with higher …

[HTML][HTML] Dual centrifugation as a novel and efficient method for the preparation of lipodisks

S Ali, JK Koehler, L Silva, L Gedda, U Massing… - International Journal of …, 2024 - Elsevier
Polyethylene glycol (PEG)-stabilized lipodisks have emerged as innovatiive, promising
nanocarriers for several classes of drugs. Prior research underscores the important role of …

Photoactive Parietin-loaded nanocarriers as an efficient therapeutic platform against triple-negative breast cancer

AM Ayoub, MS Atya, AM Abdelsalam, J Schulze… - International journal of …, 2023 - Elsevier
The application of photodynamic therapy has become more and more important in
combating cancer. However, the high lipophilic nature of most photosensitizers limits their …