The mediodorsal thalamus: an essential partner of the prefrontal cortex for cognition

S Parnaudeau, SS Bolkan, C Kellendonk - Biological psychiatry, 2018 - Elsevier
Deficits in cognition are a core feature of many psychiatric conditions, including
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …

Oxidative stress in schizophrenia: an integrated approach

BKY Bitanihirwe, TUW Woo - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
Oxidative stress has been suggested to contribute to the pathophysiology of schizophrenia.
In particular, oxidative damage to lipids, proteins, and DNA as observed in schizophrenia is …

Review of thalamocortical resting-state fMRI studies in schizophrenia

M Giraldo-Chica, ND Woodward - Schizophrenia research, 2017 - Elsevier
Brain circuitry underlying cognition, emotion, and perception is abnormal in schizophrenia.
There is considerable evidence that the neuropathology of schizophrenia includes the …

Potential metabolite markers of schizophrenia

J Yang, T Chen, L Sun, Z Zhao, X Qi, K Zhou… - Molecular …, 2013 - nature.com
Schizophrenia is a severe mental disorder that affects 0.5–1% of the population worldwide.
Current diagnostic methods are based on psychiatric interviews, which are subjective in …

The role of the thalamus in schizophrenia from a neuroimaging perspective

G Pergola, P Selvaggi, S Trizio, A Bertolino… - … & Biobehavioral Reviews, 2015 - Elsevier
The thalamus is a crucial node for brain physiology and part of functional and structural
pathways relevant for schizophrenia. Relatively few imaging studies on schizophrenia have …

Executive function, neural circuitry, and genetic mechanisms in schizophrenia

DP Eisenberg, KF Berman - Neuropsychopharmacology, 2010 - nature.com
After decades of research aimed at elucidating the pathophysiology and etiology of
schizophrenia, it has become increasingly apparent that it is an illness knowing few …

PCP: from pharmacology to modelling schizophrenia

BJ Morris, SM Cochran, JA Pratt - Current opinion in pharmacology, 2005 - Elsevier
Phencyclidine has attracted the attention of neuroscientists for many years because of its
ability to produce, in humans, a range of symptoms remarkably similar to those of patients …

The energy metabolism dysfunction in psychiatric disorders postmortem brains: focus on proteomic evidence

GS Zuccoli, VM Saia-Cereda, JM Nascimento… - Frontiers in …, 2017 - frontiersin.org
Psychiatric disorders represent a great medical and social challenge and people suffering
from these conditions face many impairments regarding personal and professional life. In …

The thalamus and schizophrenia: current status of research

W Byne, EA Hazlett, MS Buchsbaum, E Kemether - Acta neuropathologica, 2009 - Springer
The thalamus provides a nodal link for multiple functional circuits that are impaired in
schizophrenia (SZ). Despite inconsistencies in the literature, a meta analysis suggests that …

Low-frequency BOLD fluctuations demonstrate altered thalamocortical connectivity in schizophrenia

RC Welsh, AC Chen, SF Taylor - Schizophrenia bulletin, 2010 - academic.oup.com
The thalamus plays a central and dynamic role in information transmission and processing
in the brain. Multiple studies reveal increasing association between schizophrenia and …