Cerebral palsy, which occurs in two to three out of 1,000 live births, has multiple etiologies
resulting in brain injury that affects movement, posture, and balance. The movement …

Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes …

This review aimed to examine the existing evidence about interventions proposed for the
treatment of clinical chorioamnionitis, with the goal of developing an evidence-based …

Importance Preeclampsia during pregnancy has been linked to an increased risk of cerebral
palsy in offspring. Less is known about the role of preeclampsia in other …

The placenta functions as a shield against infection of the fetus. The innate and adaptive
immune defenses of the developing fetus are poorly equipped to fight infections. Infection by …

Converging evidence from clinical and preclinical studies suggests that fetal vulnerability to
adverse prenatal exposures increases the risk for neuropsychiatric diseases such as autism …

Preterm birth is a major contributor to neonatal morbidity and mortality. Complications of
prematurity such as bronchopulmonary dysplasia (BPD, affecting the lung), pulmonary …

Background The independent risk for neurodevelopmental impairments attributed to
chorioamnionitis in premature infants remains controversial. Delayed brain maturation or …

Preterm newborns are exposed to several risk factors for developing brain injury. Clinical
studies have suggested that the presence of intrauterine infection is a consistent risk factor …

The preterm newborn is at significant risk of neural injury and impaired neurodevelopment.
Infants with mild or no evidence of injury may also be at risk of altered brain development …