To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …

Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent
and treat various diseases. To function in vivo, mRNA requires safe, effective and stable …

RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Recent medical advances have exploited the ability to address a given disease at the
underlying level of transcription and translation. These treatment paradigms utilize nucleic …

In the past few years, there has been increasing focus on the use of messenger RNA
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …

Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …

Over the past decade, messenger RNA (mRNA) has emerged as potent and flexible platform
for the development of novel effective cancer immunotherapies. Advances in non-viral gene …

This review provides a comparison of the theoretical issues and experimental findings for
plasmid DNA and mRNA vaccine technologies. While both have been under development …