Bacterial resistance to antimicrobial agents

MF Varela, J Stephen, M Lekshmi, M Ojha, N Wenzel… - Antibiotics, 2021 - mdpi.com
Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …

Lipid-based antimicrobial delivery-systems for the treatment of bacterial infections

DY Wang, HC Van der Mei, Y Ren, HJ Busscher… - Frontiers in …, 2020 - frontiersin.org
Many nanotechnology-based antimicrobials and antimicrobial-delivery-systems have been
developed over the past decades with the aim to provide alternatives to antibiotic treatment …

The food production environment and the development of antimicrobial resistance in human pathogens of animal origin

M Lekshmi, P Ammini, S Kumar, MF Varela - Microorganisms, 2017 - mdpi.com
Food-borne pathogens are a serious human health concern worldwide, and the emergence
of antibiotic-resistant food pathogens has further confounded this problem. Once-highly …

Dissemination and prevalence of plasmid-mediated high-level tigecycline resistance gene tet (X4)

S Zhang, J Wen, Y Wang, M Wang, R Jia… - Frontiers in …, 2022 - frontiersin.org
With the large-scale use of antibiotics, antibiotic resistant bacteria (ARB) continue to rise,
and antibiotic resistance genes (ARGs) are regarded as emerging environmental pollutants …

Functional and structural roles of the major facilitator superfamily bacterial multidrug efflux pumps

S Kumar, M Lekshmi, A Parvathi, M Ojha, N Wenzel… - Microorganisms, 2020 - mdpi.com
Pathogenic microorganisms that are multidrug-resistant can pose severe clinical and public
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …

Bioactive natural products from Bacteroidetes

S Brinkmann, MS Spohn, TF Schäberle - Natural product reports, 2022 - pubs.rsc.org
Covering: up to end of January 2022 Bacteria representing the phylum Bacteroidetes
produce a diverse range of natural products, including polyketides, peptides and lactams …

UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes

MYX Lim, G LaMonte, M Lee, C Reimer, BH Tan… - Nature …, 2016 - nature.com
A molecular understanding of drug resistance mechanisms enables surveillance of the
effectiveness of new antimicrobial therapies during development and deployment in the …

Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens

MF Varela, J Stephen, D Bharti, M Lekshmi, S Kumar - Biomedicines, 2023 - mdpi.com
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …

Biodegradation of tylosin in swine wastewater by Providencia stuartii TYL-Y13: Performance, pathway, genetic background, and risk assessment

J Yang, Z Zhao, M Wang, K Yu, T Zhang, H Lin… - Journal of Hazardous …, 2022 - Elsevier
Microbial bioremediation offers a solution to the problem of residual antibiotics in
wastewater associated with animal farms. Efficient degradation of antibiotic residues …

Microbial resistance: The role of efflux pump superfamilies and their respective substrates

ÍR Garcia, FA de Oliveira Garcia, PS Pereira… - Life Sciences, 2022 - Elsevier
The microorganism resistance to antibiotics has become one of the most worrying issues for
science due to the difficulties related to clinical treatment and the rapid spread of diseases …