In the last decades, organoselenium compounds gained interest due to their important
biological features. However, the lack of solubility, which characterizes most of them, makes …

The discovery and synthetic applications of novel organoselenium compounds and their
reactions proceeded rapidly during the past fifty years and such processes are now carried …

There is an urgent need to develop safer and more effective modalities for the treatment of a
wide range of pathologies due to the increasing rates of drug resistance, undesired side …

An efficient methodology for the regioselective Sonogashira cross-coupling of 9-substituted
2, 8-diiodopurines has been developed. Regioselectivity is governed by the nature of the …

The 5-substituted 2-selenouridines are natural components of the bacterial tRNA
epitranscriptome. Because selenium-containing biomolecules are redox-active entities, the …

Selenosugars are interesting targets of organic synthesis as they would possess potential
biological activities. However, 4-selenotherofuranose derivatives, which have trans …

Intrigued by the biological activity of 2′‐C‐methylribofuranosyl nucleosides, and
ribavirin/acadesine, based on the bioisosteric rationale between oxygen and selenium, we …

When sulfur (S)-, selenium (Se)-, or tellurium (Te)-containing chalcogen compounds are
administrated to living organisms, they are Absorbed, Distributed to the whole body …

We report a facile method to synthesize novel alkyl selanyl [1, 2, 4] triazolo [4, 3‐a]
pyrimidine heterocyclic scaffolds. A diverse library of selenide derivatives has been …

Nucleoside analogues have emerged over the last decades as a well-established platform
to treat cancer and viral infections. This chapter describes the discovery and chemical …