Cooperation between SIX1 and DHX9 transcriptionally regulates integrin-focal adhesion signaling mediated metastasis and sunitinib resistance in KIRC
S Huang, J Hu, M Hu, Y Hou, B Zhang, J Liu, X Liu… - Oncogene, 2024 - nature.com
High invasive capacity and acquired tyrosine kinase inhibitors (TKI) resistance of kidney
renal clear cell carcinoma (KIRC) cells remain obstacles to prolonging the survival time of …
renal clear cell carcinoma (KIRC) cells remain obstacles to prolonging the survival time of …
Advances in ex vivo expansion of hematopoietic stem and progenitor cells for clinical applications
A Branco, J Rayabaram, CC Miranda… - … in Bioengineering and …, 2024 - frontiersin.org
As caretakers of the hematopoietic system, hematopoietic stem cells assure a lifelong supply
of differentiated populations that are responsible for critical bodily functions, including …
of differentiated populations that are responsible for critical bodily functions, including …
Implications of ITCH-mediated ubiquitination of SIX1 on CDC27-cyclinB1 signaling in nasopharyngeal carcinoma
Z Lin, W Cai, Y Sun, B Han, Y Hu, S Huang, J Li… - Scientific Reports, 2024 - nature.com
Nasopharyngeal carcinoma (NPC) presents a significant medical challenge due to its high
incidence rate and poor prognosis, which are attributed primarily to tumor metastasis and …
incidence rate and poor prognosis, which are attributed primarily to tumor metastasis and …
Kinetics of cancer metastasis
VP Zhdanov - Biosystems, 2024 - Elsevier
The formation of metastases during cancer is now considered to be induced by migrating
metastatic stem cells (MetSCs) in preexisting niches or niches induced by MetSCs or tumor …
metastatic stem cells (MetSCs) in preexisting niches or niches induced by MetSCs or tumor …
Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells
A Goodspeed, A Bodlak, AB Duffy, S Nelson-Taylor… - bioRxiv, 2024 - biorxiv.org
Ewing sarcoma is the second most common bone cancer in children, accounting for 2% of
pediatric cancer diagnoses. Patients who present with metastatic disease at the time of …
pediatric cancer diagnoses. Patients who present with metastatic disease at the time of …