The role of pro-Inflammatory cytokines in the pathogenesis of cardiovascular disease

H Zhang, NS Dhalla - International Journal of Molecular Sciences, 2024 - mdpi.com
With cardiovascular disease (CVD) being a primary source of global morbidity and mortality,
it is crucial that we understand the molecular pathophysiological mechanisms at play …

Emerging role of adipocyte dysfunction in inducing heart failure among obese patients with prediabetes and known diabetes mellitus

AE Berezin, AA Berezin, M Lichtenauer - Frontiers in cardiovascular …, 2020 - frontiersin.org
Adipose tissue dysfunction is a predictor for cardiovascular (CV) events and heart failure
(HF) in patient population with obesity, metabolic syndrome, and known type 2 diabetes …

[PDF][PDF] Role of interleukins in heart failure with reduced ejection fraction.

OA Segiet, A Piecuch, Ł Mielańczyk… - Anatolian Journal of …, 2019 - jag.journalagent.com
Heart failure (HF) is the leading cause of morbidity and mortality in developed countries, and
it is the primary cause of mortality in the elderly worldwide. The processes of inflammatory …

Astragaloside IV Exerts a Myocardial Protective Effect against Cardiac Hypertrophy in Rats, Partially via Activating the Nrf2/HO‐1 Signaling Pathway

P Nie, F Meng, J Zhang, X Wei… - Oxidative medicine and …, 2019 - Wiley Online Library
Previous evidence suggested that astragaloside IV (ASIV) had a cardioprotective effect, but
the potential mechanisms were undetermined. This study is aimed at validating the …

High exogenous antioxidant, restorative treatment (heart) for prevention of the six stages of heart failure: the heart diet

RB Singh, J Fedacko, D Pella, G Fatima, G Elkilany… - Antioxidants, 2022 - mdpi.com
The exact pathophysiology of heart failure (HF) is not yet known. Western diet, characterized
by highly sweetened foods, as well as being rich in fat, fried foods, red meat and processed …

Chronic heart failure: a disease of the brain

RB Singh, K Hristova, J Fedacko, G El-Kilany… - Heart Failure …, 2019 - Springer
The underlying mechanism for clinical and biochemical manifestations of chronic heart
failure (HF) may be due in part to neurohumoral adaptations, such as activation of the renin …

Gene expression and levels of IL-6 and TNFα in PBMCs correlate with severity and functional class in patients with chronic heart failure

V Eskandari, AA Amirzargar, MJ Mahmoudi… - Irish Journal of Medical …, 2018 - Springer
Background Evidence shows that proinflammatory cytokines are important determinants of
assessment of severity and prognosis of chronic heart failure (CHF). Aims We investigated …

Pre‐heart failure at 2D‐and 3D‐speckle tracking echocardiography: A comprehensive review

RB Singh, FB Sozzi, J Fedacko, K Hristova… - …, 2022 - Wiley Online Library
Chronic heart failure (CHF) has different stages and includes pre‐HF (PHF), a state of high
risk of developing myocardial dysfunction and advanced CHF. Some major behavioral risk …

Effects of Antioxidant-rich Indo-mediterranean Foods on Pre-heart Failure: Results from the Meta-analysis of Randomized Controlled Trials.

RB Singh, T Takahashi, G Fatima… - The Open …, 2020 - benthamopen.com
Background: The role of different diets and nutrients in the pathogenesis of cardiac
dysfunction is controversial. However, it is well known that the Western diet has pro …

[PDF][PDF] Beyond drug therapy, nutritional perspectives in the management of chronic heart failure

G Elkilany, RB Singh, K Hristova, B Milovanovic… - World Heart …, 2015 - researchgate.net
Recently, Singh et al. have re-emphasized the role of nutritional modulators among patients
with chronic heart failure (CHF) because these patients may suffer from weight loss as well …