Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …

Cholesterol in the circulation is mostly transported in an esterified form as a component of
lipoproteins. The majority of these cholesteryl esters are produced in nascent, discoidal high …

Hyperalphalipoproteinemia (HALP) is a lipid disorder characterized by elevated plasma
high-density lipoprotein cholesterol (HDL-C) levels above the 90th percentile of the …

Phospholipid transfer protein (PLTP) is one of the major modulators of lipoprotein
metabolism and atherosclerosis development in humans; however, we still do not quite …

Abstract Purpose of Review Phospholipid transfer protein (PLTP), a member of lipid transfer
protein family, is an important protein involved in lipid metabolism in the circulation. This …

Cholesterol homeostasis is of central importance for life. Therefore, cells have developed a
divergent set of pathways to meet their cholesterol needs. In this review, we focus on the …

The ability to accept cholesterol from cells and to promote reverse cholesterol transport
(RCT) represents the best characterized antiatherogenic function of HDL. Studies carried out …

Background and aims Atherosclerosis progression and regression studies are related to its
prevention and treatment. Although we have gained extensive knowledge on germline …

Plasma phospholipid transfer protein (PLTP) is a risk factor for cardiovascular diseases.
Sphingosine-1-phosphate (S1P), carried by high-density lipoprotein (HDL), is a potent lipid …

Background and aims Cholesteryl ester transfer protein (CETP) inhibitor-mediated induction
of HDL-cholesterol has no effect on the protection from cardiovascular disease (CVD) …