Polyamine and ethanolamine metabolism in bacteria as an important component of nitrogen assimilation for survival and pathogenicity
S Krysenko, W Wohlleben - Medical Sciences, 2022 - mdpi.com
Nitrogen is an essential element required for bacterial growth. It serves as a building block
for the biosynthesis of macromolecules and provides precursors for secondary metabolites …
for the biosynthesis of macromolecules and provides precursors for secondary metabolites …
[HTML][HTML] Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp
S Krysenko, W Wohlleben - Microorganisms, 2024 - pmc.ncbi.nlm.nih.gov
The natural soil environment of Streptomyces is characterized by variations in the availability
of nitrogen, carbon, phosphate and sulfur, leading to complex primary and secondary …
of nitrogen, carbon, phosphate and sulfur, leading to complex primary and secondary …
Genomic and chemical decryption of the Bacteroidetes phylum for its potential to biosynthesize natural products
S Brinkmann, M Kurz, MA Patras, C Hartwig… - Microbiology …, 2022 - Am Soc Microbiol
With progress in genome sequencing and data sharing, 1,000 s of bacterial genomes are
publicly available. Genome mining—using bioinformatics tools in terms of biosynthetic gene …
publicly available. Genome mining—using bioinformatics tools in terms of biosynthetic gene …
Enhanced Natamycin production by Streptomyces natalensis in shake-flasks and stirred tank bioreactor under batch and fed-batch conditions
EA Elsayed, MA Farid, HA El-Enshasy - BMC biotechnology, 2019 - Springer
Background Natamycin is an antifungal polyene macrolide antibiotic with wide applications
in health and food industries. Currently, it is the only antifungal food additive with the GRAS …
in health and food industries. Currently, it is the only antifungal food additive with the GRAS …
A metagenomic view of novel microbial and metabolic diversity found within the deep terrestrial biosphere at DeMMO: A microbial observatory in South Dakota, USA
The deep terrestrial subsurface is a large and diverse microbial habitat and vast repository
of biomass. However, in relation to its size and physical heterogeneity we have limited …
of biomass. However, in relation to its size and physical heterogeneity we have limited …
Bursts in biosynthetic gene cluster transcription are accompanied by surges of natural compound production in the myxobacterium Sorangium sp.
A better understanding of the genetic regulation of the biosynthesis of microbial compounds
could accelerate the discovery of new biologically active molecules and facilitate their …
could accelerate the discovery of new biologically active molecules and facilitate their …
Salt‐enhanced cultivation as a morphology engineering tool for filamentous actinomycetes: Increased production of labyrinthopeptin A1 in Actinomadura namibiensis
S Tesche, R Rösemeier‐Scheumann… - Engineering in Life …, 2019 - Wiley Online Library
Salt‐enhanced cultivation as a morphology engineering tool for the filamentous
actinomycete Actinomadura namibiensis was evaluated in 500‐mL shaking flasks (working …
actinomycete Actinomadura namibiensis was evaluated in 500‐mL shaking flasks (working …
Manipulation and epigenetic control of silent biosynthetic pathways in actinobacteria
S Karimian, N Farahmandzad… - World Journal of …, 2024 - Springer
Most biosynthetic gene clusters (BGCs) of Actinobacteria are either silent or expressed less
than the detectable level. The non-genetic approaches including biological interactions …
than the detectable level. The non-genetic approaches including biological interactions …
Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus
Streptomyces albidoflavus J1074 is a popular and genetically tractable platform strain used
for drug discovery and production via the expression of heterologous biosynthetic gene …
for drug discovery and production via the expression of heterologous biosynthetic gene …
Solid phase microextraction as a powerful alternative for screening of secondary metabolites in actinomycetes
VR Acquaro Junior, JP Rodrigues… - Journal of Mass …, 2019 - Wiley Online Library
Actinobacteria are one of the most promising producers of medically and industrially
relevant secondary metabolites. However, screening of such compounds in actinobacteria …
relevant secondary metabolites. However, screening of such compounds in actinobacteria …