Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical
interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast …

The efficient spread of malaria from infected humans to mosquitoes is a major challenge for
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …

There are no licensed vaccines against Plasmodium vivax. We conducted two phase 1/2a
clinical trials to assess two vaccines targeting P. vivax Duffy-binding protein region II …

Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …

The Plasmodium liver stage represents a vulnerable therapeutic target to prevent disease
progression as the parasite resides in the liver before clinical representation caused by …

Despite the high burden of Plasmodium vivax malaria in South Asian countries, the genetic
diversity of circulating parasite populations is not well described. Determinants of …

CRISPR/Cas9 approaches are revolutionizing our ability to perform functional genomics
across a wide range of organisms, including the Plasmodium parasites that cause malaria …

Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

Plasmodium vivax is responsible for most of the malaria infections outside Africa and is
currently the predominant malaria parasite in countries under elimination programs. P. vivax …

Controlled human malaria infection (CHMI) provides a highly informative means to
investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of …