Fatty acids as antibiofilm and antivirulence agents

P Kumar, JH Lee, H Beyenal, J Lee - Trends in microbiology, 2020 - cell.com
Fatty acids (FAs) have emerged as a potential alternative to conventional antibiotics. Since
many microbes respond differently to a variety of natural and synthetic FAs, substantial …

The potential of fatty acids and their derivatives as antifungal agents: A review

A Guimarães, A Venâncio - Toxins, 2022 - mdpi.com
Fungal contamination presents several problems: in humans, health issues arise from
infections with opportunistic filamentous fungi and yeast, while in food, fungi cause spoilage …

Antibiofilm and antifungal activities of medium‐chain fatty acids against Candida albicans via mimicking of the quorum‐sensing molecule farnesol

JH Lee, YG Kim, SK Khadke, J Lee - Microbial Biotechnology, 2021 - Wiley Online Library
Candida biofilms are tolerant to conventional antifungal therapeutics and the host immune
system. The transition of yeast cells to hyphae is considered a key step in C. albicans biofilm …

Alterations in gut microbiome and metabolomics in chronic hepatitis B infection-associated liver disease and their impact on peripheral immune response

Y Shen, SD Wu, Y Chen, XY Li, Q Zhu, K Nakayama… - Gut …, 2023 - Taylor & Francis
Gut dysbiosis has been reported in chronic hepatitis B (CHB) infection, however its role in
CHB progression and antiviral treatment remains to be clarified. Herein, the present study …

Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

Q Liu, B Li, Y Li, Y Wei, B Huang, J Liang, Z You, Y Li… - Gut, 2022 - gut.bmj.com
Objective Multiple clinical similarities exist between IgG4-related sclerosing cholangitis
(IgG4-SC) and primary sclerosing cholangitis (PSC), and while gut dysbiosis has been …

Antibiofilm and antivirulence efficacy of myrtenol enhances the antibiotic susceptibility of Acinetobacter baumannii

A Selvaraj, A Valliammai, C Sivasankar, M Suba… - Scientific reports, 2020 - nature.com
Acinetobacter baumannii (AB) is rising as a human pathogen of critical priority worldwide as
it is the leading cause of chronic opportunistic infections in healthcare settings and the …

Palmitic Acid Inhibits the Virulence Factors of Candida tropicalis: Biofilms, Cell Surface Hydrophobicity, Ergosterol Biosynthesis, and Enzymatic Activity

KG Prasath, H Tharani, MS Kumar… - Frontiers in …, 2020 - frontiersin.org
Biofilm is the fortitude of Candida species infections which eventually causes candidiasis in
human. C. tropicalis is one of the predominant Candida species commonly found in systemic …

Piperine Impedes Biofilm Formation and Hyphal Morphogenesis of Candida albicans

A Priya, SK Pandian - Frontiers in microbiology, 2020 - frontiersin.org
Candida albicans is the primary etiological agent associated with the pathogenesis of
candidiasis. Unrestricted growth of C. albicans in the oral cavity may lead to oral candidiasis …

[HTML][HTML] Sapindus mukorossi Gaertn. and its bioactive metabolite oleic acid impedes methicillin-resistant Staphylococcus aureus biofilm formation by down regulating …

A Selvaraj, A Valliammai, M Premika, A Priya… - Microbiological …, 2021 - Elsevier
Plants are boon to the mankind due to plenty of metabolites with medicinal values. Though
plants have traditionally been used to treat various diseases, their biological values are not …

Proteomic analysis uncovers the modulation of ergosterol, sphingolipid and oxidative stress pathway by myristic acid impeding biofilm and virulence in Candida …

KG Prasath, S Sethupathy, SK Pandian - Journal of proteomics, 2019 - Elsevier
Candida albicans, a dimorphic opportunistic fungus is known to form robust biofilm and
commonly associated with superficial and life threatening systemic infections. The repertoire …