Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Fucosylation is a biological process broadly observed in vertebrates, invertebrates, plants,
bacteria, and fungi. Fucose moieties on cell-surface glycans are increasingly recognized as …

Haptoglobin (Hp) belongs to the family of acute-phase plasma proteins and represents the
most important plasma detoxifier of hemoglobin (Hb). The basic Hp molecule is a tetrameric …

N‐glycosylation is a ubiquitous protein modification, and N‐glycosylation profiles are
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …

N‐glycome analysis in total plasma or serum yields information about the levels and
glycosylation patterns of major plasma glycoproteins, including immunoglobulins, acute …

Acute phase proteins (APPs) are a group of circulating plasma proteins which undergo
changes quantitatively or qualitatively at the time of inflammation. Many of these APPs are …

The tetrasaccharide structures Siaα2, 3Galβ1, 3 (Fucα1, 4) GlcNAc and Siaα2, 3Galβ1, 4
(Fucα1, 3) GlcNAc constitute the epitopes of the carbohydrate antigens sialyl-Lewis a (sLea) …

Changes in glycosylation readily occur in cancer and other disease states. Thanks to recent
advances in the development of analytical techniques and instrumentation, especially in …

Background & Aims Biomarkers are needed for early detection of Crohn's disease (CD) and
ulcerative colitis (UC) or to predict patient outcomes. Glycosylation is a common and …