Melatonin: a “Higgs boson” in human reproduction

S Dragojevic Dikic, AM Jovanovic, S Dikic… - Gynecological …, 2015 - Taylor & Francis
As the Higgs boson could be a key to unlocking mysteries regarding our Universe,
melatonin, a somewhat mysterious substance secreted by the pineal gland primarily at night …

Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer

BV Jardim-Perassi, AS Arbab, LC Ferreira, TF Borin… - PloS one, 2014 - journals.plos.org
As neovascularization is essential for tumor growth and metastasis, controlling angiogenesis
is a promising tactic in limiting cancer progression. Melatonin has been studied for their …

[HTML][HTML] Melatonin on hypothyroidism and gonadal development in rats: a review

YML de Albuquerque, WE da Silva… - JBRA Assisted …, 2020 - ncbi.nlm.nih.gov
We evaluated the evidence in research on the effects of melatonin on hypothyroidism and
gonadal development. According to the World Health Organization, thyroid disorders due to …

RNA-Seq transcriptome analysis shows anti-tumor actions of melatonin in a breast cancer xenograft model

BV Jardim-Perassi, PA Alexandre, NM Sonehara… - Scientific reports, 2019 - nature.com
Melatonin is a pleiotropic anti-cancer molecule that controls cancer growth by multiple
mechanisms. RNA-Seq can potentially evaluate therapeutic response and its use in …

Effects of melatonin alone or associated with acyclovir on the suppressive treatment of recurrent genital herpes: a prospective, randomized, and double-blind study

CL Roa, J Cipolla-Neto, RJ Reiter, IM Linhares… - Biomedicines, 2023 - mdpi.com
Suppressive therapy of recurrent genital herpes is a challenge, and melatonin may be an
alternative. Objective: To evaluate the action of melatonin, acyclovir, or the association of …

[HTML][HTML] Melatonin influences on steroidogenic gene expression in the ovary of pinealectomized rats

CC Maganhin, RS Simoes, LFP Fuchs, GRS Sasso… - Fertility and …, 2014 - Elsevier
Objective To analyze the expression of genes related to steroidogenesis in the ovary of
pinealectomized rats. Design Experimental research. Setting University research laboratory …

Evaluation of melatonin treatment in primary culture of canine mammary tumors

JR Lopes, LB Maschio… - Oncology …, 2015 - spandidos-publications.com
Mammary neoplasias are the most common tumors observed in female dogs. Identification
of these tumors is valuable in order to identify beneficial therapeutic agents as alternative …

Effects of melatonin in rats in the initial third stage of pregnancy exposed to sub-lethal doses of herbicides

LL de Almeida, ÁAC Teixeira, AF Soares… - Acta histochemica, 2017 - Elsevier
Exposure to the herbicides Paraquat (PQ) and Roundup® may cause cell lesions due to an
increase in oxidative stress levels in different biological systems, even in the reproductive …

[PDF][PDF] Effect of polyethylene glycol microspheres adsorbed with melatonin on oxidative stress and viscosity of cervical mucus samples infected with human …

AC de Melo Cotrim, EL França, ACH França… - Biointerface Res. Appl …, 2020 - academia.edu
The interfaces of hormones and endogenous molecules associated with nanostructured
materials is one of the ways to evaluate the therapeutic potential. Melatonin is a …

Immunohistochemical expression of melatonin receptor MT1 and glucose transporter GLUT1 in human breast cancer

TB de Castro, AL Mota… - Anti-Cancer Agents …, 2018 - ingentaconnect.com
Background: Breast cancer is a heterogeneous disease and is the leading cause of cancer-
related deaths among women. Even after diagnosis, the prognosis cannot be concluded …