Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

V Bronte, S Brandau, SH Chen, MP Colombo… - Nature …, 2016 - nature.com
Myeloid-derived suppressor cells (MDSCs) have emerged as major regulators of immune
responses in cancer and other pathological conditions. In recent years, ample evidence …

Recent advances in the mechanisms and treatment of immune thrombocytopenia

D Provan, JW Semple - EBioMedicine, 2022 - thelancet.com
Primary immune thrombocytopenia is an autoimmune disease associated with a reduced
peripheral blood platelet count. The phenotype is variable with some patients suffering no …

Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

H Alshetaiwi, N Pervolarakis, LL McIntyre, D Ma… - Science …, 2020 - science.org
Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the
capacity to suppress adaptive immune responses during cancer. It remains elusive how …

The nature of myeloid-derived suppressor cells in the tumor microenvironment

V Kumar, S Patel, E Tcyganov, DI Gabrilovich - Trends in immunology, 2016 - cell.com
Myeloid-derived suppressor cells (MDSC) are one of the major components of the tumor
microenvironment. The main feature of these cells is their potent immune suppressive …

Current concepts and advances in graft-versus-host disease immunology

GR Hill, BC Betts, V Tkachev, LS Kean… - Annual review of …, 2021 - annualreviews.org
Worldwide, each year over 30,000 patients undergo an allogeneic hema-topoietic stem cell
transplantation with the intent to cure high-risk hematologic malignancy, immunodeficiency …

Myeloid-derived suppressor cells in the tumor microenvironment

M Dysthe, R Parihar - Tumor Microenvironment: Hematopoietic Cells–Part …, 2020 - Springer
Myeloid-derived suppressor cells (MDSCs) represent a heterogenous population of
immature myeloid cells capable of modulating immune responses. In the context of cancer …

Coordinated regulation of myeloid cells by tumours

DI Gabrilovich, S Ostrand-Rosenberg… - Nature Reviews …, 2012 - nature.com
Myeloid cells are the most abundant nucleated haematopoietic cells in the human body and
are a collection of distinct cell populations with many diverse functions. The three groups of …

Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies

F Hossain, AA Al-Khami, D Wyczechowska… - Cancer immunology …, 2015 - AACR
Myeloid-derived suppressor cells (MDSC) promote tumor growth by inhibiting T-cell
immunity and promoting malignant cell proliferation and migration. The therapeutic potential …

Myeloid-derived suppressor cells: critical cells driving immune suppression in the tumor microenvironment

KH Parker, DW Beury, S Ostrand-Rosenberg - Advances in cancer …, 2015 - Elsevier
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many …

Ablative tumor radiation can change the tumor immune cell microenvironment to induce durable complete remissions

A Filatenkov, J Baker, AMS Mueller, J Kenkel… - Clinical Cancer …, 2015 - AACR
Purpose: The goals of the study were to elucidate the immune mechanisms that contribute to
desirable complete remissions of murine colon tumors treated with single radiation dose of …