Natural products targeting macroautophagy signaling in hepatocellular carcinoma therapy: Recent evidence and perspectives

Y Chen, X Tan, W Zhang, Y Li, X Deng… - Phytotherapy …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC), presently the second leading cause of global cancer‐
related mortality, continues to pose significant challenges in the realm of medical oncology …

Natural-product-mediated autophagy in the treatment of various liver diseases

G Fan, F Li, P Wang, X Jin, R Liu - International Journal of Molecular …, 2022 - mdpi.com
Autophagy is essential for the maintenance of hepatic homeostasis, and autophagic
malfunction has been linked to the pathogenesis of substantial liver diseases. As a popular …

Phosphatidylethanolamines link ferroptosis and autophagy during appressorium formation of rice blast fungus

Q Liu, R Long, C Lin, X Bi, Z Liang… - Molecular Plant …, 2024 - Wiley Online Library
A cell death pathway, ferroptosis, occurs in conidial cells and is critical for formation and
function of the infection structure, the appressorium, in the rice blast fungus Magnaporthe …

m6A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer

R Zheng, Y Yu, L Lv, Y Zhang, H Deng, J Li… - Experimental Cell …, 2023 - Elsevier
Abstract N 6-methyladenosine RNA (m 6 A) is the most extensive epigenetic modification in
mRNA and influences tumor progression. However, the role of m 6 A regulators and specific …

Targeting selective autophagy in CNS disorders by small-molecule compounds

Y Zheng, Z Zhou, M Liu, Z Chen - Pharmacology & Therapeutics, 2024 - Elsevier
Autophagy functions as the primary cellular mechanism for clearing unwanted intracellular
contents. Emerging evidence suggests that the selective elimination of intracellular …

DSCI: a database of synthetic biology components for innate immunity and cell engineering decision-making processes

C Zhang, T Chen, Z Li, Q Lu, X Luo, S Cai, J Zhou… - Advanced …, 2024 - Springer
Although significant progress of clinical strategy has been made in gene editing and cell
engineering in immunotherapy, it is now apparent that design and modification in terms of …