The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

E Buzzetti, M Pinzani, EA Tsochatzis - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

Non-alcoholic fatty liver disease and the interface between primary and secondary care

EA Tsochatzis, PN Newsome - The lancet Gastroenterology & …, 2018 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) has a prevalence of 25–30% in unselected
populations and has become the main reason for referrals to hepatology services. From the …

Factors associated with histologic response in adult patients with nonalcoholic steatohepatitis

R Loomba, AJ Sanyal, KV Kowdley, N Terrault… - Gastroenterology, 2019 - Elsevier
Background & Aims Nonalcoholic steatohepatitis (NASH) is a leading cause of liver
transplantation, and many trials are underway to evaluate potential therapies. The farnesoid …

[HTML][HTML] Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection

P Parikh, JD Ryan, EA Tsochatzis - Annals of translational …, 2017 - ncbi.nlm.nih.gov
Chronic hepatitis B virus (HBV) infection is a major cause of liver morbidity and mortality
worldwide. While a proportion of the 250 million individuals chronically infected with HBV …

Evaluating the association of serum ferritin and hepatic iron with disease severity in non‐alcoholic fatty liver disease

E Buzzetti, S Petta, R Manuguerra, TV Luong… - Liver …, 2019 - Wiley Online Library
Abstract Background & Aims Hyperferritinemia, with or without increased hepatic iron,
represents a common finding in non‐alcoholic fatty liver disease (NAFLD). However, it is …

Role of serum uric acid and ferritin in the development and progression of NAFLD

R Lombardi, G Pisano, S Fargion - International journal of molecular …, 2016 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), tightly linked to the metabolic syndrome (MS), has
emerged as a leading cause of chronic liver disease worldwide. Since it is potentially …

Referral pathways for patients with NAFLD based on non‐invasive fibrosis tests: Diagnostic accuracy and cost analysis

C Crossan, A Majumdar, A Srivastava… - Liver …, 2019 - Wiley Online Library
Background/aims Non‐invasive fibrosis tests (NITs) can be used to triage non‐alcoholic fatty
liver disease (NAFLD) patients at risk of advanced fibrosis (AF). We modelled and …

Non-invasive testing and risk-stratification in patients with MASLD

M Zoncapè, A Liguori, EA Tsochatzis - European Journal of Internal …, 2024 - Elsevier
The development and validation of non-invasive fibrosis tests (NITs) has changed clinical
practice in Hepatology over the last 15 years. Metabolic associated steatotic liver disease …

Non-invasive measurement of hepatic fibrosis by transient elastography: a narrative review

L Rinaldi, C Giorgione, A Mormone, F Esposito… - Viruses, 2023 - mdpi.com
Transient elastography by FibroScan®(Echosens, Paris, France) is a non-invasive method
that can provide a reliable measurement of liver fibrosis through the evaluation of liver …

[HTML][HTML] Simple noninvasive scores are clinically useful to exclude, not predict, advanced fibrosis: a study in Turkish patients with biopsy-proven nonalcoholic fatty liver …

E Kaya, A Bakir, HT Kani, CO Demirtas… - Gut and liver, 2020 - ncbi.nlm.nih.gov
Methods The diagnostic performance of each noninvasive test according to previously
identified cutoff points indicating low and high risk for advanced fibrosis was determined in …