Reactivity to smoking-related cues may be an important factor that precipitates relapse in
smokers who are trying to quit. The neurobiology of smoking cue reactivity has been …

Rewards are both “liked” and “wanted,” and those 2 words seem almost interchangeable.
However, the brain circuitry that mediates the psychological process of “wanting” a particular …

Neuroimaging studies on cue reactivity have substantially contributed to the understanding
of addiction. In the majority of studies drug cues were presented in the visual modality …

Results: Prerandomization smoking cues vs nonsmoking cues activated the ventral striatum
and medial orbitofrontal cortex (t= 3.77) and elicited subjective reports of craving (P=. 006) …

The identification and functional understanding of the neurocircuitry that mediates alcohol
and drug effects that are relevant for the development of addictive behavior is a fundamental …

Cigarette smoke contains nicotine and toxic chemicals and may cause significant
neurochemical and anatomical brain changes. Voxel-based morphometry studies have …

Nicotine addiction is highly prevalent in current society and is often comorbid with other
diseases. In the central nervous system, nicotine acts as an agonist for nicotinic …

Functional neuroimaging has become an increasingly common tool for studying drug
craving. Furthermore, functional neuroimaging studies, which have addressed an incredibly …

Variation at a single nucleotide polymorphism in the μ-opioid receptor gene (OPRM1),
A118G (Asn40Asp), may moderate naltrexone (NTX) effects in alcohol dependence. Both …

This chapter summarizes genetic factors that contribute to variation in nicotine
pharmacokinetics and nicotine's pharmacological action in the central nervous system …