Ischaemic stroke
Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …
[HTML][HTML] The role of the nitric oxide pathway in brain injury and its treatment—from bench to bedside
PS Garry, M Ezra, MJ Rowland, J Westbrook… - Experimental …, 2015 - Elsevier
Nitric oxide (NO) is a key signalling molecule in the regulation of cerebral blood flow. This
review summarises current evidence regarding the role of NO in the regulation of cerebral …
review summarises current evidence regarding the role of NO in the regulation of cerebral …
Can animal models of disease reliably inform human studies?
HB Van der Worp, DW Howells, ES Sena… - PLoS …, 2010 - journals.plos.org
Can Animal Models of Disease Reliably Inform Human Studies? | PLOS Medicine Skip to main
content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special Issues …
content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special Issues …
Nitric oxide and peroxynitrite in health and disease
P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation
Treatments for acute ischaemic stroke continue to evolve after the superior value of
endovascular thrombectomy was confirmed over systemic thrombolysis. Unfortunately …
endovascular thrombectomy was confirmed over systemic thrombolysis. Unfortunately …
[HTML][HTML] Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial …
ENOS Trial Investigators - The Lancet, 2015 - Elsevier
Background High blood pressure is associated with poor outcome after stroke. Whether
blood pressure should be lowered early after stroke, and whether to continue or temporarily …
blood pressure should be lowered early after stroke, and whether to continue or temporarily …
Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase …
Background High blood pressure is common in acute stroke and is a predictor of poor
outcome; however, large trials of lowering blood pressure have given variable results, and …
outcome; however, large trials of lowering blood pressure have given variable results, and …
Publication bias in reports of animal stroke studies leads to major overstatement of efficacy
The consolidation of scientific knowledge proceeds through the interpretation and then
distillation of data presented in research reports, first in review articles and then in textbooks …
distillation of data presented in research reports, first in review articles and then in textbooks …
The janus face of VEGF in stroke
SJ Geiseler, C Morland - International journal of molecular sciences, 2018 - mdpi.com
The family of vascular endothelial growth factors (VEGFs) are known for their regulation of
vascularization. In the brain, VEGFs are important regulators of angiogenesis …
vascularization. In the brain, VEGFs are important regulators of angiogenesis …
Dietary nitrate supplementation improves rowing performance in well-trained rowers
H Bond, L Morton, AJ Braakhuis - … journal of sport …, 2012 - journals.humankinetics.com
Increased plasma nitrate concentrations from dietary sources of nitrate have proven to
benefit exercise performance. Beetroot (BR) contains relatively high levels of nitrate (NO 3−) …
benefit exercise performance. Beetroot (BR) contains relatively high levels of nitrate (NO 3−) …