Advances in Nanocarrier Systems for Overcoming Formulation Challenges of Curcumin: Current Insights
Curcumin, an organic phenolic molecule that is extracted from the rhizomes of Curcuma
longa Linn, has undergone extensive evaluation for its diverse biological activities in both …
longa Linn, has undergone extensive evaluation for its diverse biological activities in both …
Intranasal delivery of darunavir-loaded mucoadhesive in situ gel: Experimental design, in vitro evaluation, and pharmacokinetic studies
The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low
perfusion of the drug to the brain. The objective of the current investigation was to design …
perfusion of the drug to the brain. The objective of the current investigation was to design …
Adenosine Conjugated Docetaxel Nanoparticles—Proof of Concept Studies for Non-Small Cell Lung Cancer
Non-small cell lung cancer, a molecularly diverse disease, is the most prevalent cause of
cancer mortality globally. Increasing understanding of the clinicopathology of the disease …
cancer mortality globally. Increasing understanding of the clinicopathology of the disease …
Formulation and evaluation of self-nanoemulsifying drug delivery system derived tablet containing sertraline
Being a biopharmaceutics classification system class II drug, the absorption of sertraline
from the gut is mainly limited by its poor aqueous solubility. The objective of this …
from the gut is mainly limited by its poor aqueous solubility. The objective of this …
Intranasal administration of dolutegravir-loaded nanoemulsion-based in situ gel for enhanced bioavailability and direct brain targeting
Dolutegravir's therapeutic effectiveness in the management of neuroAIDS is mainly limited
by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as …
by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as …
Qbd-based approach to optimize niosomal gel of levosulpiride for transdermal drug delivery
Poor aqueous solubility besides extensive hepatic first effect significantly decreases the oral
absorption of levosulpiride, which in turn minimizes its therapeutic effectiveness. Niosomes …
absorption of levosulpiride, which in turn minimizes its therapeutic effectiveness. Niosomes …
Lung targeted lipopolymeric microspheres of dexamethasone for the treatment of ARDS
Acute respiratory distress syndrome (ARDS), a catastrophic illness of multifactorial etiology,
involves a rapid upsurge in inflammatory cytokines that leads to hypoxemic respiratory …
involves a rapid upsurge in inflammatory cytokines that leads to hypoxemic respiratory …
Protective effects of curcumin against spinal cord injury
Background In parallel with population aging, the prevalence of neurological and
neurodegenerative diseases has been dramatically increasing over the past few decades …
neurodegenerative diseases has been dramatically increasing over the past few decades …
Development and validation of an LC-MS/MS method for the assessment of Isoxazole, a bioactive analogue of curcumin in rat plasma: Application to a …
A novel Isoxazole (ISO) analog of curcumin is synthesized from curcumin and described as
having a better pharmacological activity than curcumin, such as anti-cancer, anti-malarial …
having a better pharmacological activity than curcumin, such as anti-cancer, anti-malarial …
[HTML][HTML] QbD driven targeted pulmonary delivery of dexamethasone-loaded chitosan microspheres: Biodistribution and pharmacokinetic study
Inhaling drugs, on the other hand, is limited mainly by the natural mechanisms of the
respiratory system, which push drug particles out of the lungs or make them inefficient once …
respiratory system, which push drug particles out of the lungs or make them inefficient once …