Recent advances and challenges of RT-PCR tests for the diagnosis of COVID-19

M Teymouri, S Mollazadeh, H Mortazavi… - … -Research and Practice, 2021 - Elsevier
Since the outbreak of the novel severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2), the control of virus spread has remained challenging given the pitfalls of the current …

[HTML][HTML] Recent advances in nanotechnology-based diagnosis and treatments of human osteosarcoma

M Barani, M Mukhtar, A Rahdar, S Sargazi, S Pandey… - Biosensors, 2021 - mdpi.com
Osteosarcoma (OSA) is a type of bone cancer that begins in the cells that form bones. OSA
is a rare mesenchymal bone neoplasm derived from mesenchymal stem cells. Genome …

Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods

A Poustforoosh, H Hashemipour, B Tüzün… - Biophysical …, 2021 - Elsevier
Introduction Despite all the efforts to treat COVID-19, no particular cure has been found for
this virus. Since developing antiviral drugs is a time-consuming process, the most effective …

Development and challenges of antimicrobial peptide delivery strategies in bacterial therapy: A review

L Yao, Q Liu, Z Lei, T Sun - International Journal of Biological …, 2023 - Elsevier
The escalating global prevalence of antimicrobial resistance poses a critical threat,
prompting concerns about its impact on public health. This predicament is exacerbated by …

Recent advances in Bio-conjugated nanocarriers for crossing the Blood-Brain Barrier in (pre-) clinical studies with an emphasis on vesicles

A Poustforoosh, MH Nematollahi… - Journal of Controlled …, 2022 - Elsevier
The brain is one of the most challenging organs for drug delivery. It is preserved by the
blood-brain barrier (BBB), which controls the transport of components into and out of the …

[HTML][HTML] Nanomaterials for the diagnosis and treatment of urinary tract infections

M Qindeel, M Barani, A Rahdar, R Arshad… - Nanomaterials, 2021 - mdpi.com
The diagnosis and treatment of urinary tract infections (UTIs) remain challenging due to the
lack of convenient assessment techniques and to the resistance to conventional …

[HTML][HTML] Iron chelator or iron supplement consumption in COVID-19? The role of iron with severity infection

A Bastin, H Shiri, S Zanganeh, S Fooladi… - Biological trace element …, 2021 - Springer
Iron is a trace element that is used to replicate the virus and has a role in the vital functions
of the body and the host's innate immune system. The mechanism of iron in COVID-19 …

Covalent organic frameworks and metal-organic frameworks against pathogenic viruses and antibiotic-resistant bacteria: Diagnostic and therapeutic applications

MH Nematollahi, E Mostafavi, S Iravani - Journal of Environmental …, 2023 - Elsevier
Antimicrobial resistance and antiviral infections statistics show that the number of global
cases has been exponentially increasing; thus there is an unmet need for developing …

[HTML][HTML] Insights gained from RNA editing targeted by the CRISPR-Cas13 family

L Liu, DS Pei - International Journal of Molecular Sciences, 2022 - mdpi.com
Clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated
protein (Cas) systems, especially type II (Cas9) systems, have been widely developed for …

[HTML][HTML] Nanomaterials for the diagnosis and treatment of head and neck cancers: a review

G Ruiz-Pulido, DI Medina, M Barani, A Rahdar… - Materials, 2021 - mdpi.com
Head and neck cancer (HNC) is a category of cancers that typically arise from the nose-,
mouth-, and throat-lining squamous cells. The later stage of HNC diagnosis significantly …