[HTML][HTML] Ionizing radiation-induced circulatory and metabolic diseases

S Tapio, MP Little, JC Kaiser, N Impens… - Environment …, 2021 - Elsevier
Risks to health are the prime consideration in all human situations of ionizing radiation
exposure and therefore of relevance to radiation protection in all occupational, medical, and …

Radioprotection and radiomitigation: from the bench to clinical practice

E Obrador, R Salvador, JI Villaescusa, JM Soriano… - Biomedicines, 2020 - mdpi.com
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …

A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line

A Soubry, C Hoyo, RL Jirtle, SK Murphy - Bioessays, 2014 - Wiley Online Library
Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …

MicroRNAs: predictors and modifiers of chemo-and radiotherapy in different tumour types

R Hummel, DJ Hussey, J Haier - European journal of cancer, 2010 - Elsevier
MicroRNAs (miRNAs) represent a class of naturally occurring small non-coding RNA
molecules. They regulate gene expression at the post-transcriptional level and control …

Induction of epigenetic alterations by dietary and other environmental factors

JC Mathers, G Strathdee, CL Relton - Advances in genetics, 2010 - Elsevier
Dietary and other environmental factors induce epigenetic alterations which may have
important consequences for cancer development. This chapter summarizes current …

Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria

I Szumiel - International journal of radiation biology, 2015 - Taylor & Francis
Purpose: To review the data concerning the role of endogenously generated reactive
oxygen species (ROS) in the non-targeted ionizing radiation (IR) effects and in …

Radiation-induced bystander effects: what are they, and how relevant are they to human radiation exposures?

BJ Blyth, PJ Sykes - Radiation research, 2011 - meridian.allenpress.com
The term radiation-induced bystander effect is used to describe radiation-induced biological
changes that manifest in unirradiated cells remaining within an irradiated cell population …

Radiation damage and radioprotectants: new concepts in the era of molecular medicine

MI Koukourakis - The British journal of radiology, 2012 - academic.oup.com
Exposure to ionising radiation results in mutagenesis and cell death, and the clinical
manifestations depend on the dose and the involved body area. Reducing carcinogenesis in …

[HTML][HTML] Adaptive radiation-induced epigenetic alterations mitigated by antioxidants

AJ Bernal, DC Dolinoy, D Huang, DA Skaar… - The FASEB …, 2013 - ncbi.nlm.nih.gov
Humans are exposed to low-dose ionizing radiation (LDIR) from a number of environmental
and medical sources. In addition to inducing genetic mutations, there is concern that LDIR …

Systemic mechanisms and effects of ionizing radiation: A new⿿ old⿿ paradigm of how the bystanders and distant can become the players

Z Nikitaki, IV Mavragani, DA Laskaratou, V Gika… - Seminars in cancer …, 2016 - Elsevier
Exposure of cells to any form of ionizing radiation (IR) is expected to induce a variety of DNA
lesions, including double strand breaks (DSBs), single strand breaks (SSBs) and oxidized …