[HTML][HTML] The driving mechanism and targeting value of mimicry between vascular endothelial cells and tumor cells in tumor progression

X Ma, Z Geng, S Wang, Z Yu, T Liu, S Guan… - Biomedicine & …, 2023 - Elsevier
The difficulty and poor prognosis of malignant tumor have always been a difficult problem to
be solved. The internal components of solid tumor are complex, including tumor cells …

VE-Cadherin in cancer-associated angiogenesis: A deceptive strategy of blood vessel formation

D Delgado-Bellido, FJ Oliver… - International Journal of …, 2023 - mdpi.com
Tumor growth depends on the vascular system, either through the expansion of blood
vessels or novel adaptation by tumor cells. One of these novel pathways is vasculogenic …

Cadherin‐5 facilitated the differentiation of human induced pluripotent stem cells into sinoatrial node‐like pacemaker cells by regulating β‐catenin

W Zhang, F Wang, L Yin, Y Tang… - Journal of Cellular …, 2024 - Wiley Online Library
Our study was conducted to investigate whether cadherin‐5 (CDH5), a vascular endothelial
cell adhesion glycoprotein, could facilitate the differentiation of human induced pluripotent …

Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3

Y Liu, G Li, J Ning, Y Zhao - Oncology Letters, 2024 - spandidos-publications.com
Abstract Ginsenoside Rg3 (GS‑Rg3), a sterol molecule isolated from ginseng, has
demonstrated various immunological properties, including inhibition of cancer cell …

[HTML][HTML] MAML3-fusions modulate vascular and immune tumour microenvironment and confer high metastatic risk in pheochromocytoma and paraganglioma

M Monteagudo, B Calsina, ME Salazar-Hidalgo… - Best Practice & …, 2024 - Elsevier
Pheochromocytomas and paragangliomas are rare neuroendocrine tumours. Around 20-
25% of patients develop metastases, for which there is an urgent need of prognostic markers …

Poly (ethylenimine)-Cyclodextrin-Based Cationic Polymer Mediated HIF-1α Gene Delivery for Hindlimb Ischemia Treatment

J Li, Z Lu, L Xu, J Wang, S Qian, Q Hu… - ACS Applied Bio …, 2024 - ACS Publications
Hindlimb ischemia is a common disease worldwide featured by the sudden decrease in limb
perfusion, which usually causes a potential threat to limb viability and even amputation or …

Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin

L Wu, J Xiao, D Yi, H Ding, R Wang, Z Duan… - Journal of Translational …, 2024 - Springer
Background Although the long-term prognosis of papillary thyroid cancer (PTC) is favorable,
distant metastasis significantly compromises the prognosis and quality of life for patients with …

TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving …

AV Gaikwad, MS Eapen, S Dey, P Bhattarai… - Journal of Clinical …, 2024 - mdpi.com
Background: We have previously reported that endothelial-to-mesenchymal transition
(EndMT) is an active process in patients with idiopathic pulmonary fibrosis (IPF) contributing …

State-of-the-Art Differentiation Protocols for Patient-Derived Cardiac Pacemaker Cells

E Torre, ME Mangoni, A Lacampagne, AC Meli… - International Journal of …, 2024 - mdpi.com
Human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes raise the possibility of
generating pluripotent stem cells from a wide range of human diseases. In the cardiology …

Engineered in vivo and in vitro tumor model recapitulates vasculogenic mimicry signatures in melanoma

Q Shuai, X Xu, Y Liang, Z Halbiyat, X Lu… - Bioengineering & …, 2024 - Wiley Online Library
Vasculogenic mimicry (VM) describes a process by which tumor cells formed a novel
microcirculation pattern in an endothelial cell‐free manner. Clinically, VM is associated with …