Tissue factor (TF) is the high-affinity receptor and cofactor for factor (F) VII/VIIa. The TF-FVIIa
complex is the primary initiator of blood coagulation and plays an essential role in …

Venous thromboembolism (VTE) is a significant health problem in the general population
but especially in cancer patients. In this review, we discuss the epidemiology and burden of …

Objective: Patients with coronavirus disease 2019 (COVID-19) have a high rate of
thrombosis. We hypothesized that severe acute respiratory syndrome coronavirus 2 infection …

Background Enumeration of extracellular vesicles has clinical potential as a biomarker for
disease. In biological samples, the smallest and largest vesicles typically differ 25‐fold in …

Background Plasma and other body fluids contain membranous extracellular vesicles (EVs),
which are considered to derive from activated or apoptotic cells. EVs participate in …

Blood contains microparticles (MPs) derived from a variety of cell types, including platelets,
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …

Platelets are essential for clotting in the blood and maintenance of normal hemostasis.
Under pathologic conditions such as atherosclerosis, vascular injury often results in …

Venous thrombosis is a leading cause of morbidity and mortality in industrialized countries,
especially in the elderly. Many risk factors have been identified for venous thrombosis that …

Extracellular vesicles (EVs) are well-established mediators of cell-to-cell communication.
EVs can be released by every cell type and they can be classified into three major groups …

Patients with cancer have an increased risk for venous thrombosis. Interestingly, different
cancer types have different rates of thrombosis, with pancreatic cancer having one of the …