Curcumin, a yellow pigment from Curcuma longa, is a major component of turmeric and is
commonly used as a spice and food-coloring agent. It is also used as a cosmetic and in …

A wide variety of phenolic substances derived from spice possess potent antimutagenic and
anticarcinogenic activities. Examples are curcumin, a yellow colouring agent, contained in …

The enzyme xanthine oxidoreductase (XOR) catalyses the last step of purine degradation in
the highest uricotelic primates as a rate-limiting enzyme in nucleic acid catabolism. Although …

This paper is a comprehensive review of the effects of bioactive polyphenolic compounds
commonly found in many fruits and vegetables on cancer. These include the pheniolic acids …

Substantial experimental evidence exists which implicates both oxygen-and organic-free
radical intermediates in the multiple stages of chemical carcinogenesis. This overview …

Multiple lines of evidences suggest that oxidative stress induced by reactive oxygen species
are closely related to multi-stage carcinogenesis. Polyphenols, a group of chemicals with …

The molybdo–flavoenzymes are structurally related proteins that require a molybdopterin
cofactor and FAD for their catalytic activity. In mammals, four enzymes are known: xanthine …

Oxidative stress imposed by reactive oxygen species (ROS) plays a crucial role in the
pathophysiology associated with neoplasia, atherosclerosis, and neurodegenerative …

High-risk human papillomaviruses (HPVs) are etiologically implicated in human cervical
cancer. Two viral genes, E6 and E7, are commonly found expressed in these cancer cells …

The two-step initiation-promotion protocol for the induction of skin tumors in mice is a
convenient model to elucidate what molecular events are involved in the multistage process …