Histamine (HA) is a potent mediator that plays a central role in inflammation and allergy,
acting through four G-protein-coupled receptors (ie H1–H4). HA is an accepted promoter of …

Background and Purpose The histamine H4 receptor has a primary role in inflammatory
functions, making it an attractive target for the treatment of asthma and refractory …

Eosinophils are the predominant inflammatory cells recruited to allergic airways. In this
article, we show that human and murine eosinophils express SWAP-70, an intracellular RAC …

In recent years a non-neuronal cholinergic system has been described in immune cells,
which is often usually activated during the course of inflammatory processes. To date, it is …

Dendritic cells (DC) are able to present extracellular antigens associated with the molecules
of the major histocompatibility complex class I. In a previous work, we demonstrated that the …

Objective and design: The modulation of antigen uptake and activation of dendritic cells
(DCs) by histamine may function as a regulator of inflammation. Therefore, we sought to …

Background: Histamine is an important mediator in the development of allergic reactions.
The biological effects of histamine are mediated through four histaminergic receptors. In …

The most common diseases affecting respiratory tract are bronchial asthma and chronic
obstructive pulmonary disease (COPD). Both pathologies involve the genesis of an …

Diferentes avances en neurociencia e inmunología han determinado la interacción
bidireccional entre los sistemas nervioso e inmune. La Acetilcolina (ACh) es el …

Dendritic cells (DCs) are professional antigen presenting cells. They are present at sites of
high antigen exposure. After capturing an antigen they mature and migrate to the draining …