Triazolization of Enolizable Ketones with Primary Amines: A General Strategy toward Multifunctional 1, 2, 3‐Triazoles

R Prakash, T Opsomer, W Dehaen - The Chemical Record, 2021 - Wiley Online Library
The development of metal‐free syntheses toward 1, 2, 3‐triazoles has been a burgeoning
research area throughout the past decade. Despite the numerous advances, the scarceness …

Bicyclic 1, 3a, 6a-triazapentalene chromophores: Synthesis, spectroscopy and their use as fluorescent sensors and probes

Y Wang, T Opsomer, W Dehaen - Chemosensors, 2021 - mdpi.com
The 1, 3a, 6a-triazapentalene (TAP) is an aromatic heterocyclic fluorescent dye with
interesting features such as its small size, large Stokes shift, solvatochromism, and emission …

1, 3a, 6a-Triazapentalene derivatives as photo-induced cytotoxic small fluorescent dyes

D Tsuji, A Nakayama, R Yamamoto… - Communications …, 2023 - nature.com
Abstract 1, 3a, 6a-Triazapentalene (TAP) is a compact fluorescent chromophore whose
fluorescence properties vary greatly depending on the substituents on the TAP ring. This …

Palladium-Catalyzed Arylations towards 3, 6-Diaryl-1, 3a, 6a-triazapentalenes and Evaluation of Their Fluorescence Properties

Y Wang, T Opsomer, F de Jong, D Verhaeghe… - Molecules, 2024 - mdpi.com
Methyl 4-(1, 3a, 6a-triazapentalen-3-yl) benzoate (TAP1) shows interesting properties as a
small molecule fluorophore. In the search for post-functionalization methods, palladium …

Pyridazino-1, 3a, 6a-triazapentalenes as versatile fluorescent probes: impact of their post-functionalization and application for cellular imaging

D Sirbu, N Chopin, I Martinić, M Ndiaye… - International Journal of …, 2021 - mdpi.com
Pyridazino-1, 3a, 6a-triazapentalenes (PyTAP) are compact fused 6/5/5 tricyclic scaffolds
which exhibit promising fluorescent properties. Chemically stable, they can be post …

A Multicomponent approach toward angularly fused/linear bitriazoles: a cascade cornforth rearrangement and triazolization

S Pulikkal Veettil… - The Journal of …, 2021 - ACS Publications
A multicomponent reaction of triazoloketones, primary amines, and 4-nitrophenyl azide was
developed for the synthesis of hitherto unknown angularly fused/linear bitriazoles. The two …

4a Nucleophilic Aromatic Substitution

MR Crampton - Organic Reaction Mechanisms 2020, 2024 - Wiley Online Library
Analogies between the mechanisms of electrophilic substitution and nucleophilic
substitution have been discussed. Theoretical calculations, involving aromaticity …

[PDF][PDF] Bicyclic 1, 3a, 6a-Triazapentalene Chromophores: Synthesis, Spectroscopy and Their Use as Fluorescent Sensors and Probes. Chemosensors 2021, 9, 16

Y Wang, T Opsomer, W Dehaen - doi. org/10.3390 …, 2021 - lirias.kuleuven.be
The 1, 3a, 6a-triazapentalene (TAP) is an aromatic heterocyclic fluorescent dye with
interesting features such as its small size, large Stokes shift, solvatochromism, and emission …

Molecular rearrangements

JM Coxon - Organic Reaction Mechanisms· 2013: An annual …, 2016 - Wiley Online Library
This chapter reviews pericyclic reactions in general and reactions where a cascade of
concerted processes with transition states representing superpositions of two pericyclic …

Oxidation and Reduction

KK Banerji - Organic Reaction Mechanisms 2020, 2024 - Wiley Online Library
N, N‐Dialkyl aniline and aminonaphthalenes undergo oxidative cross‐coupling with
phenols and naphthols using a Cr‐salen catalyst (1) under aerobic conditions. A mechanism …