Interactions of angiotensin-converting enzyme-2 (ACE2) and SARS-CoV-2 spike receptor-binding domain (RBD): a structural perspective

S Borkotoky, D Dey, Z Hazarika - Molecular biology reports, 2023 - Springer
Abstract Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has
caused millions of infections and deaths worldwide since its discovery in late 2019 in …

Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to …

D Pflumm, A Seidel, F Klein, R Groß, L Krutzke… - Frontiers in …, 2023 - frontiersin.org
A multitude of alterations in the old immune system impair its functional integrity. Closely
related, older individuals show, for example, a reduced responsiveness to severe acute …

tANCHOR fast and cost-effective cell-based immunization approach with focus on the receptor-binding domain of SARS-CoV-2

H Bernauer, A Schlör, J Maier, N Bannert… - Biology Methods and …, 2023 - academic.oup.com
Successful induction of antibodies in model organisms like mice depends strongly on
antigen design and delivery. New antigen designs for immunization are helpful for …

[HTML][HTML] Ferritin-binding and ubiquitination-modified mRNA vaccines induce potent immune responses and protective efficacy against SARS-CoV-2

T Yu, CC Zhang, JH Xing, T Zhang, ZQ Xu, YX Di… - International …, 2024 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) incessantly
engenders mutating strains via immune escape mechanisms, substantially escalating the …