HFIP in organic synthesis

HF Motiwala, AM Armaly, JG Cacioppo… - Chemical …, 2022 - ACS Publications
1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Transition-metal-catalyzed C–S, C–Se, and C–Te bond formations via cross-coupling and atom-economic addition reactions. Achievements and challenges

IP Beletskaya, VP Ananikov - Chemical Reviews, 2022 - ACS Publications
In the present review, we discuss recent progress in the field of C–Z bond formation
reactions (Z= S, Se, Te) catalyzed by transition metals. Two complementary methodologies …

[HTML][HTML] A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

C Sambiagio, D Schönbauer, R Blieck… - Chemical Society …, 2018 - pubs.rsc.org
The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

Electrochemical Radical Selenylation of Alkenes and Arenes via Se–Se Bond Activation

L Sun, L Wang, H Alhumade, H Yi, H Cai, A Lei - Organic Letters, 2021 - ACS Publications
A novel electrochemical radical selenylation of alkenes and activated arenes without
external oxidants is reported. The diselenide was fully transformed into Se-centered radicals …

Expedient C–H chalcogenation of indolines and indoles by positional-selective copper catalysis

P Gandeepan, J Koeller, L Ackermann - ACS Catalysis, 2017 - ACS Publications
A versatile protocol for the C–H chalcogenation of indolines and indoles by means of copper
catalysis was established. The C–H functionalization occurred selectively at the C7 position …

Visible-light-mediated aerobic selenation of (hetero) arenes with diselenides

QB Zhang, YL Ban, PF Yuan, SJ Peng, JG Fang… - Green …, 2017 - pubs.rsc.org
The first visible-light driven aerobic oxidation for the direct selenation of (hetero) arenes has
been developed at room temperature, providing an eco-friendly, atom-economical protocol …

Chelation-assisted transition metal-catalysed C–H chalcogenylations

W Ma, N Kaplaneris, X Fang, L Gu, R Mei… - Organic Chemistry …, 2020 - pubs.rsc.org
The development of convenient and mild chalcogenylation reactions for the preparation of
unsymmetrical diaryl sulfides and diaryl selenides has received significant attention in …

Electrochemical regioselective C–H selenylation of 2 H-indazole derivatives

S Lin, X Cheng, B Hasimujiang, Z Xu, F Li… - Organic & Biomolecular …, 2022 - pubs.rsc.org
Selenium-substituted heteroarenes are biologically active compounds and useful building
blocks. In this study, we have developed a metal-and oxidant-free, environmentally friendly …

Direct electrochemical selenylation/cyclization of alkenes: Access to functionalized benzheterocycles

X Cheng, B Hasimujiang, Z Xu, H Cai… - The Journal of …, 2021 - ACS Publications
A catalyst-free, environmentally friendly, and efficient electrochemical selenylation/
cyclization of alkenes has been developed with moderate to excellent yields. This …

Recent advances in C–H bond functionalization with ruthenium-based catalysts

KS Singh - Catalysts, 2019 - mdpi.com
The past decades have witnessed rapid development in organic synthesis via catalysis,
particularly the reactions through C–H bond functionalization. Transition metals such as Pd …