Skeletal tissue is highly innervated. Although different types of nerves have been recently
identified in the bone, the crosstalk between bone and nerves remains unclear. In this …

5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous
system and peripheral structures, acting also as a hormone in platelets. Although its …

Neuroimmune cross-talk participates in intestinal tissue homeostasis and host defense.
However, the matrix of interactions between arrays of molecularly defined neuron subsets …

The intestine harbors a large population of resident eosinophils, yet the function of intestinal
eosinophils has not been explored. Flow cytometry and whole-mount imaging identified …

Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …

Interactions between the enteric nervous system (ENS) and intestinal epithelium are thought
to play a vital role in intestinal homeostasis. How the ENS monitors the frontier with …

Highlights•Enteric glial cells (EGCs) are required for maintenance of gut tissue
homeostasis.•GFAP+ EGCs regulate the health of the intestinal epithelial barrier.•EGCs …

Abstract Muscularis Externa Macrophages (ME-Macs) and enteric glial cells (EGCs) are
closely associated cell types in the bowel wall, and important interactions are thought to …

Since their discovery, innate lymphoid cells (ILCs) have been described as the innate
counterpart of the T cells. Indeed, ILCs and T cells share many features including their …

Scientific and philosophical accounts of cognition and perception have traditionally focused
on the brain and external sense organs. The extended view of embodied cognition suggests …