Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

Abstract Design of experiment (DoE) is a powerful statistical technique used for variable
screening and optimization. It is based on the simultaneous variation of multiple factors with …

Nanoscale engineering is one of the novel methods to cure multitudes of diseases, such as
types of cancers, neurological disorders, and infectious illnesses. Viruses can play a vital …

Virus-like particles (VLPs) have emerged as a powerful scaffold for antigen presentation and
delivery strategies. Compared to single protein-based therapeutics, quality assessment …

To improve the detection capability of the nanoscale samples, we proposed a new approach
to integrating acousto-microfluidics and Raman spectroscopy. Different design parameters …

Direct at line monitoring of live virus particles in commercial manufacturing of vaccines is
challenging due to their small size. Detection of malformed or damaged virions with reduced …

Insect cells have shown a high versatility to produce multiple recombinant products. The
ease of culture, low contamination risk with human pathogens and high expression capacity …

The nature of enveloped virus-like particles (VLPs) has triggered high interest in their
application to different research fields, including vaccine development. The baculovirus …

Virus‐like particles (VLPs) offer great promise in the field of nanomedicine. Enveloped VLPs
are a class of these nanoparticles and their production process occurs by a budding …

High Five cells are an excellent host for the production of virus-like particles (VLPs) with the
baculovirus expression vector system (BEVS). However, the concurrent production of high …