Immune checkpoint blockade (ICB) necessitates a thorough understanding of intricate
cellular interactions within the tumor microenvironment (TME). Mesenchymal stromal cells …

Metastatic clear cell renal cell carcinoma has heterogenous tumor microenvironment (TME).
Among the metastatic lesions, pancreas metastasis is rare and controversy in treatment …

Approximately one‐third of advanced renal cell carcinoma (RCC) patients develop osteolytic
bone metastases, leading to skeletal complications. In this review, we first provide a …

Canine mucosal melanoma (CMM) is the most common oral malignancy in dogs and is
significantly more aggressive than its cutaneous counterpart (CCM), yet the reasons for this …

Background: Although the application of mesenchymal stem cells (MSCs) in engineered
medicine, such as tissue regeneration, is well known, new evidence is emerging that shows …

Introduction: Breast cancer is the leading cause of cancer-related death in Mexico, with high
mortality associated with spinal bone metastasis. We propose to standardize a murine …

Cancer progression remains a significant clinical challenge. Phenotypic adaptation by tumor
cells results in disease heterogeneity, which drives treatment resistance and immune …

Bone represents congenial soil for metastatic seeds and is frequently affected by metastasis
of multiple cancer types. The histological and molecular characteristics of bone metastases …

RGS19: A novel prognostic biomarker for tumor immunity in clear cell renal cell carcinoma
revealed through comprehensive bulk and single-cell sequencing analysis RGS19: A novel …

Unveiling FADS3 as a novel prognostic biomarker for tumor immunity in clear cell renal cell
carcinoma through comprehensive RNA and single-cell sequencing Unveiling FADS3 as a …