Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibroproliferative
alterations of the microvasculature leading to fibrosis and loss of function of the skin and …

Here, we provide important updates pertaining to the risk stratification, assessment,
diagnosis and management of SSc patients with gastrointestinal symptoms. These findings …

Background Data on the neuromodulatory effects of brain‐derived neurotrophic factor
(BDNF) in the gastrointestinal tract were recently reported, but there are still no data on the …

Background Gastrointestinal tract (GIT) involvement is a common cause of debilitating
symptoms in patients with systemic sclerosis (SSc). There are no disease modifying …

Objective To analyze the effectiveness and safety of intravenous immunoglobulin (IVIG)
given in routine care to patients with systemic sclerosis (SSc). Methods A retrospective …

Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the
gastrointestinal tract, and the severity of gastrointestinal disease in SSc correlates with high …

The identification of individuals with systemic sclerosis in an oligosymptomatic phase
preceding the very early manifestations of the disease represents a challenge in the search …

Intravenous administration of immunoglobulins has been routinely used for more than 60
years in clinical practice, developed initially as replacement therapy in immunodeficiency …

Systemic sclerosis (SSc) is a chronic, multisystem connective tissue, and autoimmune
disease with the highest case-specific mortality and complications among rheumatic …

Systemic sclerosis (SSc) is a chronic systemic disease characterized by microvasculopathy,
autoantibodies, and extensive fibrosis. Intestinal involvement is frequent in SSc and …