Covariate adjusted inference of parent‐of‐origin effects using case–control mother–child paired multilocus genotype data

K Zhang, H Zhang, H Hochner, J Chen - Genetic Epidemiology, 2021 - Wiley Online Library
It is of great interest to identify parent‐of‐origin effects (POEs) since POEs play an important
role in many human heritable disorders and human early life growth and development. POE …

Joint modeling of eQTLs and parent-of-origin effects using an orthogonal framework with RNA-seq data

S Deng, J Hardin, CI Amos, F Xiao - Human Genetics, 2020 - Springer
Extensive studies have been conducted on the analysis of genome function, especially on
the expression quantitative trait loci (eQTL). These studies offered promising results for …

Abundant Parent-of-origin Effect eQTL in Humans: The Framingham Heart Study

Y Guan, D Levy - bioRxiv, 2024 - biorxiv.org
Parent-of-origin effect (POE) is a phenomenon whereby an allele's effect on a phenotype
depends both on its allelic identity and parent from whom the allele is inherited, as …

[图书][B] Bioinformatics Methods: From Omics to Next Generation Sequencing

S Lin, D Scholtens, S Datta - 2022 - taylorfrancis.com
The past three decades have witnessed an explosion of what is now referred to as high-
dimensionalomics' data. Bioinformatics Methods: From Omics to Next Generation …

Exploring necroptosis-associated genes: implications for immune responses and therapeutic strategies in diabetic foot ulcers

M Yuan, J Sun, Z Zhao, X Hu, W Fan, H Shi, G Liu - 2024 - researchsquare.com
Diabetic foot ulcers (DFUs) are among the most severe and debilitating diabetic
complications, often leading to extremely high morbidity and mortality. Recently, increasing …

Analysis of Genetic, Parent of Origin or Treatment Effect on Gene Expression Using RNA-Seq Data in Human and Mouse

V Zhabotynsky - 2020 - search.proquest.com
RNA sequencing allows us to systematically study allelic imbalance of gene expression,
which may be due to genetic factors or genomic imprinting. In order to avoid confounding …

A statistical method for joint estimation of cis-eQTLs and parent-of-orign effects using an orthogonal framework with RNA-seq data

S Deng, F Xiao - bioRxiv, 2019 - biorxiv.org
In the past few years extensive studies have been put on the analysis of genome function,
especially on expression quantitative trait loci (eQTL) which offered promise for …