Radiation-induced lymphopenia is known for its survival significance in patients with breast
cancer treated with radiation therapy. This study aimed to evaluate the impact of …

Peffer et al. first proposed the 10-year qualification period method (ie, all donors must have
donated for at least 10 years to be qualified for the study) as a means to adjust for HDE. 29 …

Background Plateletpheresis involves platelet separation and collection from whole blood
while other blood cells are returned to the donor. Because platelets are replaced faster than …

Balancing the state and the market, the “third pillar”(ie, any association of people that is
neither public nor private) is a key sector in society. In contrast to the first two pillars (the …

Frequent plateletpheresis is associated with severe lymphopenia of uncertain clinical
significance. We assessed the functional impact of frequent platelet donations and …

Background: The World Health Organization emphasizes the importance of completely
voluntary blood donation to maintain safe and sustainable blood supplies. However, the …

Background Plateletpheresis using a leukocyte reduction system (LRS) traps donor WBCs in
the LRS chamber, which may lead to lymphopenia, especially in frequent plateletpheresis …

Older humans and animals often exhibit reduced immune responses to infection and
vaccination, and this often directly correlates to the numbers and frequency of naive T (Tn) …

Background Severe T‐cell lymphopenia of uncertain clinical significance has been
observed in frequent apheresis platelet donors. Two commonly used plateletpheresis …

Abstract In the United States, more than 2 000 000 apheresis platelet units are collected
annually from volunteer donors. Platelet donors in the United States and elsewhere are …