The incidence of type 2 diabetes (T2D) has been increasing worldwide, and diabetic kidney
disease (DKD) remains one of the leading long-term complications of T2D. Several lines of …

Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting
in elevated cost for public health systems. DN is the main cause of chronic kidney disease …

Chronic kidney disease (CKD) with type 2 diabetes (T2D) is a major public health problem,
resulting in significant cardiovascular and kidney adverse outcomes worldwide. Despite the …

As the prevalence of diabetes continues to climb, the number of individuals living with
diabetic complications will reach an unprecedented magnitude. The emergence of new …

Diabetic kidney disease (DKD) is the most common cause of end-stage kidney disease
(ESKD) in the United States. Risk factor modification, such as tight control of blood glucose …

The gastrointestinal tract—the largest endocrine network in human physiology—
orchestrates signals from the external environment to maintain neural and hormonal control …

The prevalence of diabetes is growing worldwide with an increasing morbidity and mortality
associated with the development of diabetes complications. Free radical production is a …

OBJECTIVE Dipeptidyl peptidase 4 inhibitors may have a protective effect in diabetic
nephropathy. RESEARCH DESIGN AND METHODS We studied renal outcomes of 16,492 …

Glucagon-like peptide-1 (GLP-1) is a gut incretin hormone that has an antioxidative
protective effect on various tissues. Here, we determined whether GLP-1 has a role in the …

OBJECTIVE Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may
lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin …