New trends in platinum and palladium complexes as antineoplastic agents

M Fanelli, M Formica, V Fusi, L Giorgi… - Coordination Chemistry …, 2016 - Elsevier
The discovery of cisplatin (cis-Pt (NH 3) 2 Cl 2) as an antineoplastic agent has focussed
attention on the rational design of metal complexes that can be potentially used in cancer …

Research progress in modern structure of platinum complexes

L Bai, C Gao, Q Liu, C Yu, Z Zhang, L Cai… - European journal of …, 2017 - Elsevier
Since the antitumor activity of cisplatin was discovered in 1967 by Rosenberg, platinum-
based anticancer drugs have played an important role in chemotherapy in clinic …

Platinum iodido complexes: A comprehensive overview of anticancer activity and mechanisms of action

P Štarha, J Vančo, Z Trávníček - Coordination Chemistry Reviews, 2019 - Elsevier
Platinum iodido complexes have long been recognized as synthetic intermediates of various
platinum complexes (eg, chlorido or carboxylato), including the world-wide used platinum …

Enriching Chemical Space of Bioactive Scaffolds by New Ring Systems: Benzazocines and Their Metal Complexes as Potential Anticancer Drugs

I Kuznetcova, M Ostojić, N Gligorijević… - Inorganic …, 2022 - ACS Publications
The search for new scaffolds of medicinal significance combined with molecular shape
enhances their innovative potential and continues to attract the attention of researchers …

Synthesis, characterization and biological evaluation of novel Ru (II)–arene complexes containing intercalating ligands

S Nikolić, L Rangasamy, N Gligorijević… - Journal of Inorganic …, 2016 - Elsevier
Three new ruthenium (II)–arene complexes, namely [(η 6-p-cymene) Ru (Me 2 dppz) Cl] PF
6 (1),[(η 6-benzene) Ru (Me 2 dppz) Cl] PF 6 (2) and [(η 6-p-cymene) Ru (aip) Cl] PF 6 …

Antitumor activity of organoruthenium complexes with chelate aromatic ligands, derived from 1, 10-phenantroline: synthesis and biological activity

A Savić, N Gligorijević, S Aranđelović… - Journal of Inorganic …, 2020 - Elsevier
The monocationic chloro complexes containing chelating N∩ N ligands:[(η 6-p-cymene) Ru
(L1–4) Cl]+(1–4), where L1= 4-methyl-1, 10-phenantroline, L2= dipyrido [3, 2-a: 2′, 3′-c] …

Platinum (II) iodido complexes of 7-azaindoles with significant antiproliferative effects: an old story revisited with unexpected outcomes

P Štarha, J Vančo, Z Trávníček, J Hošek, J Klusakova… - PLoS …, 2016 - journals.plos.org
A series of platinum (II) diiodido complexes containing 7-azaindole derivatives, having the
general formula cis-[PtI2 (n aza) 2](1–8), has been prepared and thoroughly characterized …

Current development of metal complexes with diamine ligands as potential anticancer agents

S Misirlic-Dencic, J Poljarevic… - Current Medicinal …, 2020 - benthamdirect.com
Background: The discovery of cisplatin and the subsequent research revealed the
importance of dinitrogen-containing moiety for the anticancer action of metal complexes …

Targeting human telomeric and c-myc G-quadruplexes with alkynylplatinum (II) terpyridine complexes under molecular crowding conditions

Z Ou, Y Wang, Y Gao, X Wang, Y Qian, Y Li… - Journal of inorganic …, 2017 - Elsevier
The interactions between alkynylplatinum (II) terpyridine complexes 1–3 and the G-
quadruplex DNA, including c-myc and telomeric quadruplex DNA, are investigated both in …

Photophysical, G-quadruplex DNA binding and cytotoxic properties of terpyridine complexes with a naphthalimide ligand

Z Ou, Y Qian, Y Gao, Y Wang, G Yang, Y Li, K Jiang… - RSC …, 2016 - pubs.rsc.org
Two novel metal complexes 2–3 (metal= PdII, PtII) have been synthesized by reacting the
corresponding tolylterpyridine complexes and the 4-aminonaphthalimide derivative 1. The …