Hybrid or recombinant protein-polymers, peptide-based biomaterials, and antibody-targeted
therapeutics are widely explored for various ocular conditions and vision correction. They …

Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research
allowing analyzes from small samples and low concentrations. This review begins with a …

We compared the metabolomic profile of aqueous humor from patients with primary open-
angle glaucoma (POAG; n= 26) with that of a group of age-and sex-matched non-POAG …

Assessing metabolomic alterations in age-related macular degeneration (AMD) can provide
insights into its pathogenesis. We compared the metabolomic profiles of the aqueous humor …

Emerging data suggest a close correlation between ambient fine particle (AFP) exposure
and eye disorders and pinpoint potential threats of AFPs to eye health in humans. However …

The lenticular fiber cells are comprised of extremely long-lived proteins while still
maintaining an active biochemical state. Dysregulation of these activities has been …

The kidney is comprised of highly complex structures that rely on self-maintenance for their
functions, and tissue repair and regeneration in renal diseases. We devised a proteomics …

Alzheimer's disease (AD) is an ageing-related neurodegenerative disease characterized
and diagnosed by deposition of insoluble amyloid-β (Aβ) plaques in the brain. The plaque …

Purpose. The present study investigated the profiles of matrix metalloproteinases (MMPs)
and tissue inhibitors of metalloproteinases (TIMPs) of the aqueous humor (AH) and plasma …

Exosomes, nanosized extracellular vesicles with a size of 30–150nm, contain many
biological materials, such as messenger RNA (mRNA), microRNA (miRNA), proteins, and …