This review is aimed at presenting the state-of-the-art of time domain (TD) functional near-
infrared spectroscopy (fNIRS). We first introduce the physical principles, the basics of …

Near-infrared spectroscopy (NIRS) measurements of cytochrome-c-oxidase (CCO) have the
potential to yield crucial information about cerebral metabolism at the patient bedside …

This review describes the unique opportunities and challenges for noninvasive optical
mapping of human brain function. Diffuse optical methods offer safe, portable, and radiation …

Functional neuroimaging commands a dominant role in current neuroscience research.
However its use in bedside clinical and certain neuro-scientific studies has been limited …

Pathophysiologic mechanisms involved in neonatal hypoxic ischemic encephalopathy (HIE)
are associated with complex changes of blood flow and metabolism. Therapeutic …

Diffuse optical imaging (DOI) is increasingly becoming a valuable neuroimaging tool when
fMRI is precluded. Recent developments in high-density diffuse optical tomography (HD …

Cerebral near-infrared spectroscopy (NIRS) oximetry may help clinicians to improve patient
treatment. However, the application of NIRS oximeters is increasingly causing confusion to …

While histological studies and conventional magnetic resonance imaging (MRI)
investigations have elucidated the trajectory of structural changes in the developing brain …

Measurements of human brain function in children are of increasing interest in cognitive
neuroscience. Many techniques for brain mapping used in children, including functional …

Little is known about cerebral blood flow, cerebral blood volume (CBV), oxygenation, and
oxygen consumption in the premature newborn brain. We combined quantitative frequency …