Metformin as an anti-inflammatory agent: a short review

R Kristófi, JW Eriksson - Journal of Endocrinology, 2021 - joe.bioscientifica.com
Metformin is a biguanide drug widely used as the initial treatment of type 2 diabetes. Despite
its widespread use, its precise mechanisms of action remain incompletely characterised. Its …

[HTML][HTML] Metformin beyond an anti-diabetic agent: A comprehensive and mechanistic review on its effects against natural and chemical toxins

A Malaekeh-Nikouei, S Shokri-Naei… - Biomedicine & …, 2023 - Elsevier
In addition to the anti-diabetic effect of metformin, a growing number of studies have shown
that metformin has some exciting properties, such as anti-oxidative capabilities, anticancer …

[HTML][HTML] Anti-diabetics and antimicrobials: Harmony of mutual interplay

WAH Hegazy, AAH Rajab, ASA Lila… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Diabetes is one of the four major non-communicable diseases, and appointed by the world
health organization as the seventh leading cause of death worldwide. The scientists have …

A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin

JN Justice, S Gubbi, AS Kulkarni, JM Bartley… - Geroscience, 2021 - Springer
We are in the midst of the global pandemic. Though acute respiratory coronavirus (SARS-
COV2) that leads to COVID-19 infects people of all ages, severe symptoms and mortality …

Cellular immunity of patients with tuberculosis combined with diabetes

P Cheng, L Wang, W Gong - Journal of immunology research, 2022 - Wiley Online Library
Tuberculosis (TB) is one of humanity's three major infectious diseases. Diabetes mellitus
(DM) is a metabolic disease characterized by hyperglycemia due to impaired insulin …

Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs

L Rodrigues, P Cravo, M Viveiros - Expert review of anti-infective …, 2020 - Taylor & Francis
ABSTRACT Introduction: In 2018, an estimated 377,000 people developed multidrug-
resistant tuberculosis (MDR-TB), urging for new effective treatments. In the last years, it has …

Modulating macrophage function to reinforce host innate resistance against Mycobacterium avium complex infection

HE Park, W Lee, S Choi, M Jung, MK Shin… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium avium complex (MAC) is the main causative agent of infectious diseases in
humans among nontuberculous mycobacteria (NTM) that are ubiquitous organisms found in …

Lactate metabolism and signaling in tuberculosis and cancer: a comparative review

D Kiran, RJ Basaraba - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Infection with Mycobacterium tuberculosis (Mtb) leading to tuberculosis (TB) disease
continues to be a major global health challenge. Critical barriers, including but not limited to …

[HTML][HTML] Situación de la comorbilidad tuberculosis y diabetes en personas adultas en el Perú, 2016-2018

C Ugarte-Gil, M Curisinche… - Revista peruana de …, 2021 - SciELO Public Health
Objetivo: Describir las características de los pacientes adultos con tuberculosis (TB) y
diabetes mellitus (DM) en el Perú, y explorar la asociación de la DM y la mortalidad en …

THP-1 cell line model for tuberculosis: a platform for in vitro macrophage manipulation

PT Shah, M Tufail, C Wu, L Xing - Tuberculosis, 2022 - Elsevier
Macrophages are large mononuclear phagocytic cells that play a vital role in the immune
response. They are present in all body tissues with extremely heterogeneous and plastic …