The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Beyond gut feelings: how the gut microbiota regulates blood pressure

FZ Marques, CR Mackay, DM Kaye - Nature Reviews Cardiology, 2018 - nature.com
Hypertension is the leading risk factor for heart disease and stroke, and is estimated to
cause 9.4 million deaths globally every year. The pathogenesis of hypertension is complex …

Periodontitis and its inflammatory changes linked to various systemic diseases: a review of its underlying mechanisms

R Bhuyan, SK Bhuyan, JN Mohanty, S Das, N Juliana… - Biomedicines, 2022 - mdpi.com
Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …

Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
Periodontitis is a common intraoral infection and is inextricably linked to systemic diseases.
Recently, the regulation between host immunologic response and periodontal pathogens …

A novel injectable piezoelectric hydrogel for periodontal disease treatment

L Roldan, C Montoya, V Solanki, KQ Cai… - … Applied Materials & …, 2023 - ACS Publications
Periodontal disease is a multifactorial, bacterially induced inflammatory condition
characterized by the progressive destruction of periodontal tissues. The successful …

[HTML][HTML] Oral microbiome and pregnancy: A bidirectional relationship

M Saadaoui, P Singh, S Al Khodor - Journal of reproductive immunology, 2021 - Elsevier
The oral cavity contains the second most complex microbial population within the human
body, with more than 700 bacterial organisms. Recent advances in Next Generation …

The contribution of the human oral microbiome to oral disease: a review

AG Morrison, S Sarkar, S Umar, STM Lee, SM Thomas - Microorganisms, 2023 - mdpi.com
The oral microbiome is an emerging field that has been a topic of discussion since the
development of next generation sequencing and the implementation of the human …

Streptococcus sanguinis biofilm formation & interaction with oral pathogens

B Zhu, LC Macleod, T Kitten, P Xu - Future microbiology, 2018 - Taylor & Francis
Caries and periodontitis are the two most common human dental diseases and are caused
by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to …

Can an infection hypothesis explain the beta amyloid hypothesis of Alzheimer's disease?

T Fulop, JM Witkowski, K Bourgade, A Khalil… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is the most frequent type of dementia. The pathological hallmarks
of the disease are extracellular senile plaques composed of beta-amyloid peptide (Aβ) and …