H Cichoż-Lach, A Michalak - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases …
N Anderson, J Borlak - Pharmacological reviews, 2008 - ASPET
Steatosis of the liver may arise from a variety of conditions, but the molecular basis for lipid droplet formation is poorly understood. Although a certain amount of lipid storage may even …
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin resistance, mitochondrial dysfunction, inflammation, and oxidative stress. As a group of …
Aliment Pharmacol Ther 31, 679–692 Summary Background Non‐alcoholic fatty liver disease affects 10–35% of the adult population worldwide; there is no consensus on its …
MND Di Minno, A Russolillo, R Lupoli… - World journal of …, 2012 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. It is the most important cause of chronic liver disease and a major independent cardiovascular …
FS Zhu, S Liu, XM Chen, ZG Huang… - World journal of …, 2008 - ncbi.nlm.nih.gov
AIM: To investigate the efficacy and safety of n-3 polyunsaturated fatty acids (PUFA) from seal oils for patients with nonalcoholic fatty liver disease (NAFLD) associated with …
Mitochondrial dysfunction and oxidative stress play a central role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). This study aimed to elucidate the mechanism (s) …
G Cavaliere, F Cimmino, G Trinchese, A Catapano… - Antioxidants, 2023 - mdpi.com
Obesity is a major risk factor for several metabolic diseases, including type 2 diabetes, hyperlipidemia, cardiovascular diseases, and brain disorders. Growing evidence suggests …
Objective: SIRT1 is an NAD+‐dependent deacetylase and its enzymatic activity may be regulated by cellular energy. SIRT1 overexpression reduces the level of oxygen …