[HTML][HTML] Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

[HTML][HTML] Oxidative stress as a crucial factor in liver diseases

H Cichoż-Lach, A Michalak - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis

N Anderson, J Borlak - Pharmacological reviews, 2008 - ASPET
Steatosis of the liver may arise from a variety of conditions, but the molecular basis for lipid
droplet formation is poorly understood. Although a certain amount of lipid storage may even …

[HTML][HTML] Progress in nonalcoholic fatty liver disease: SIRT family regulates mitochondrial biogenesis

C Zeng, M Chen - Biomolecules, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin
resistance, mitochondrial dysfunction, inflammation, and oxidative stress. As a group of …

omega‐3 fatty acids–a promising novel therapy for non‐alcoholic fatty liver disease

GS Masterton, JN Plevris… - Alimentary pharmacology …, 2010 - Wiley Online Library
Aliment Pharmacol Ther 31, 679–692 Summary Background Non‐alcoholic fatty liver
disease affects 10–35% of the adult population worldwide; there is no consensus on its …

[HTML][HTML] Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease

MND Di Minno, A Russolillo, R Lupoli… - World journal of …, 2012 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. It
is the most important cause of chronic liver disease and a major independent cardiovascular …

[HTML][HTML] Effects of n-3 polyunsaturated fatty acids from seal oils on nonalcoholic fatty liver disease associated with hyperlipidemia

FS Zhu, S Liu, XM Chen, ZG Huang… - World journal of …, 2008 - ncbi.nlm.nih.gov
AIM: To investigate the efficacy and safety of n-3 polyunsaturated fatty acids (PUFA) from
seal oils for patients with nonalcoholic fatty liver disease (NAFLD) associated with …

[HTML][HTML] Mitochondrial dysfunction in rat with nonalcoholic fatty liver: involvement of complex I, reactive oxygen species and cardiolipin

G Petrosillo, P Portincasa, I Grattagliano… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Mitochondrial dysfunction and oxidative stress play a central role in the pathophysiology of
nonalcoholic fatty liver disease (NAFLD). This study aimed to elucidate the mechanism (s) …

[HTML][HTML] From obesity-induced low-grade inflammation to lipotoxicity and mitochondrial dysfunction: altered multi-crosstalk between adipose tissue and metabolically …

G Cavaliere, F Cimmino, G Trinchese, A Catapano… - Antioxidants, 2023 - mdpi.com
Obesity is a major risk factor for several metabolic diseases, including type 2 diabetes,
hyperlipidemia, cardiovascular diseases, and brain disorders. Growing evidence suggests …

The expression of SIRT1 in nonalcoholic fatty liver disease induced by high‐fat diet in rats

XQ Deng, LL Chen, NX Li - Liver International, 2007 - Wiley Online Library
Objective: SIRT1 is an NAD+‐dependent deacetylase and its enzymatic activity may be
regulated by cellular energy. SIRT1 overexpression reduces the level of oxygen …