Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …

The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …

Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …

The metastatic organotropism has been one of the cancer's greatest mysteries since the
'seed and soil'hypothesis. Although the role of EGFR in cancer cells is well studied, the …

Long-and short-distance communication can take multiple forms. Among them are
exosomes and ectosomes, extracellular vesicles (EVs) released from the cell to deliver …

MicroRNAs regulate gene expression posttranscriptionally and function within the cells in
which they are transcribed. However, recent evidence suggests that microRNAs can be …

Inflammation plays an important role in cardiac injuries. Here, we examined the role of
miRNA in regulating inflammation and cardiac injury during myocardial infarction. We …

Mesenchymal stem cells (MSCs) have been increasingly tested experimentally and clinically
for cardiac repair. However, the underlying mechanisms remain controversial due to the …