Stop the beat to see the rhythm: excitation-contraction uncoupling in cardiac research

LM Swift, MW Kay, CM Ripplinger… - American Journal of …, 2021 - journals.physiology.org
Optical mapping is an imaging technique that is extensively used in cardiovascular
research, wherein parameter-sensitive fluorescent indicators are used to study the …

Catheter ablation of refractory ventricular fibrillation storm after myocardial infarction: a multicenter study

Y Komatsu, M Hocini, A Nogami, P Maury, P Peichl… - Circulation, 2019 - Am Heart Assoc
Background: Ventricular fibrillation (VF) storm after myocardial infarction (MI) is a life-
threatening condition that necessitates multiple defibrillations. Catheter ablation is a …

Effect of cerebrolysin on oxidative stress-induced apoptosis in an experimental rat model of myocardial ischemia

V Boshra, A Atwa - Physiology International (Acta Physiologica …, 2016 - akjournals.com
Apoptosis plays a role in the process of tissue damage after myocardial infarction (MI). This
study was designed to investigate the possible effect of cerebrolysin against apoptosis …

Effects of azumolene on arrhythmia substrate in a model of recurrent long-duration ventricular fibrillation

P Chakraborty, S Massé, MA Azam, C Thollon… - Biochemical and …, 2022 - Elsevier
Background Proarrhythmic risk of conventional anti-arrhythmic agents is linked to
unintended modulation of membrane voltage dynamics. We have demonstrated that the anti …

Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart

M Warren, KJ Sciuto, TG Taylor… - American Journal …, 2017 - journals.physiology.org
Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion
channels mediating cardiac excitability and conduction, but how this regulation translates to …

Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases: implications for arrhythmogenesis

AV Zaitsev, NS Torres, KM Cawley… - American Journal …, 2019 - journals.physiology.org
The “stress” kinases cAMP-dependent protein kinase (PKA) and calcium/calmodulin-
dependent protein kinase II (CaMKII), phosphorylate the Na+ channel Nav1. 5 subunit to …

Automatic measurement of short-term variability of repolarization to indicate ventricular arrhythmias in a porcine model of cardiac ischaemia

V Loen, A Smoczynska, A Aranda Hernandez… - Europace, 2023 - academic.oup.com
Aims An automated method for determination of short-term variability (STV) of repolarization
on intracardiac electrograms (STV-ARIauto) has previously been developed for arrhythmic …

Mechanism of action potential prolongation during metabolic inhibition in the whole rabbit heart

R Mačianskienė, I Martišienė, A Navalinskas… - Frontiers in …, 2018 - frontiersin.org
Myocardial ischemia is associated with significant changes in action potential (AP) duration,
which has a biphasic response to metabolic inhibition. Here, we investigated the mechanism …

[HTML][HTML] The benefit of prophylactic implantable cardioverter defibrillator implantation in asymptomatic heart failure patients with a reduced ejection fraction

ALCJ van der Lingen, SAJ Timmer, LJH Allaart… - The American Journal of …, 2019 - Elsevier
Recommendations for prophylactic implantable cardioverter defibrillator (ICD) implantation
in asymptomatic heart failure patients with a reduced left ventricular ejection fraction (LVEF) …

[HTML][HTML] Right Ventricular Physiology in Health and Disease: Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases …

AV Zaitsev, NS Torres, KM Cawley… - American Journal of …, 2019 - ncbi.nlm.nih.gov
The “stress” kinases cAMP-dependent protein kinase (PKA) and calcium/calmodulin-
dependent protein kinase II (CaMKII), phosphorylate the Na+ channel Nav1. 5 subunit to …