Single-cell profiling methods have had a profound impact on the understanding of cellular
heterogeneity. While genomes and transcriptomes can be explored at the single-cell level …

Electrolyte-gated silicon field-effect transistors (FETs) capable of detecting single molecules
could enable high-throughput molecular sensing chips to advance, for example, genomics …

A binary/digital method is proposed in theory for the identification of single amino acids
(AAs) in the bulk or with a few molecules from a single binary measurement. Combined with …

Proteins in the crowded environment of human cells have often been studied regarding
nonspecific interactions, misfolding, and aggregation, which may cause cellular malfunction …

A microalbuminuria level acts as a good index to screen and monitor diabetes and renal
failure. However, the urinary albumin loss after sample preservation and storage is the major …

Zusammenfassung Die Proteomanalyse von Blut-oder Urinproben ist ein
vielversprechender Ansatz zur Entdeckung neuer Biomarker, mit dem Ziel, eine endgültige …

A procedure to identify single amino acids (AAs) in the bulk or with a few molecules from a
single binary measurement is introduced. Combined with Edman degradation (or other …

A procedure to identify single amino acids (AAs) in the bulk or with a few molecules from a
single binary measurement is introduced. Combined with Edman degradation (or other …

Proteomic analysis on blood or urine samples is a promising approach for discovering novel
biomarkers, aiming to achieve a final diagnosis with less invasiveness and more feasibility …

A label-free procedure to identify single amino acids (AAs) for de novo protein sequencing is
developed in theory and simulated in part. A terminal AA cleaved from a protein/peptide, a …