Nitric oxide synthase inhibitors as potential therapeutic agents for gliomas: A systematic review

MA Merenzon, EH Arias, S Bhatia, AH Shah… - Nitric Oxide, 2023 - Elsevier
Introduction Gliomas represent the most prevalent form of brain tumors, among which
glioblastomas are the most malignant subtype. Despite advances in comprehending their …

NOS expression and NO function in glioma and implications for patient therapies

AN Tran, NH Boyd, K Walker… - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Gliomas are central nervous system tumors that primarily occur in the brain
and arise from glial cells. Gliomas include the most common malignant brain tumor in adults …

[HTML][HTML] MYBL2 is an independent prognostic marker that has tumor-promoting functions in colorectal cancer

F Ren, L Wang, X Shen, X Xiao, Z Liu… - American journal of …, 2015 - ncbi.nlm.nih.gov
The MYBL2 gene plays an important role in the genesis and progression of tumors;
however, few studies to date have defined the role of this gene in colorectal cancer (CRC) …

Upstream signaling events leading to elevated production of pro-survival nitric oxide in photodynamically-challenged glioblastoma cells

JM Fahey, W Korytowski, AW Girotti - Free Radical Biology and Medicine, 2019 - Elsevier
Nitric oxide (NO) generated endogenously by inducible nitric oxide synthase (iNOS)
promotes growth and migration/invasion of glioblastoma cells and also fosters resistance to …

Role of nitric oxide in hyper-aggressiveness of tumor cells that survive various anti-cancer therapies

AW Girotti, JF Fahey, W Korytowski - Critical Reviews in Oncology …, 2022 - Elsevier
Low level nitric oxide (NO) produced by inducible NO synthase (iNOS) in many malignant
tumors is known to play a key role in the survival and proliferation of tumor cells. NO can …

Insights on the functional dualism of nitric oxide in the hallmarks of cancer

P Panneerselvan, K Vasanthakumar… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Nitric oxide (NO), a gaseous radical, governs a variety of physiological and pathological
processes, including cancer, pro-inflammatory signalling, and vasodilation. The family of …

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

Z Hu, SA Brooks, V Dormoy, CW Hsu, HY Hsu… - …, 2015 - academic.oup.com
One of the important 'hallmarks' of cancer is angiogenesis, which is the process of formation
of new blood vessels that are necessary for tumor expansion, invasion and metastasis …

Evaluation of consistency in spheroid invasion assays

LR Cisneros Castillo, AD Oancea, C Stüllein… - Scientific reports, 2016 - nature.com
Multicellular tumor spheroids embedded in a matrix represent invaluable tools to analyze
cell invasion. Spheroid sizes and invasiveness are the main observables easily measurable …

Angiogenesis-related gene signature-derived risk score for glioblastoma: Prospects for predicting prognosis and immune heterogeneity in glioblastoma

G Wang, JQ Hu, JY Liu, XM Zhang - Frontiers in Cell and …, 2022 - frontiersin.org
Background: Glioblastoma multiforme (GBM) is the most common malignant tumor in the
central nervous system with poor prognosis and unsatisfactory therapeutic efficacy …

Amygdalin modulates prostate cancer cell adhesion and migration in vitro

J Mani, J Neuschäfer, C Resch, J Rutz… - Nutrition and …, 2020 - Taylor & Francis
The natural compound, amygdalin, is notably popular with prostate cancer patients as an
alternative or complementary treatment option. However, knowledge about its mode of …