Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Flavonols and flavones as potential anti‐inflammatory, antioxidant, and antibacterial compounds

MSS Chagas, MD Behrens… - Oxidative medicine …, 2022 - Wiley Online Library
Plant preparations have been used to treat various diseases and discussed for centuries.
Research has advanced to discover and identify the plant components with beneficial effects …

Oxidative stress and hyper-inflammation as major drivers of severe COVID-19 and long COVID: implications for the benefit of high-dose intravenous vitamin C

C Vollbracht, K Kraft - Frontiers in Pharmacology, 2022 - frontiersin.org
Oxidative stress is a pivotal point in the pathophysiology of COVID-19 and presumably also
in Long-COVID. Inflammation and oxidative stress are mutually reinforcing each other, thus …

Prevalence and impact of diabetes in hospitalized COVID‐19 patients: A systematic review and meta‐analysis

SA Bradley, M Banach, N Alvarado… - Journal of …, 2022 - Wiley Online Library
Background Diabetes is a cardiometabolic comorbidity that may predispose COVID‐19
patients to worse clinical outcomes. This study sought to determine the prevalence of …

Chronic diseases associated with increased likelihood of hospitalization and mortality in 68,913 COVID-19 confirmed cases in Spain: A population-based cohort study

A Gimeno-Miguel, K Bliek-Bueno, B Poblador-Plou… - PloS one, 2021 - journals.plos.org
Background Clinical outcomes among COVID-19 patients vary greatly with age and
underlying comorbidities. We aimed to determine the demographic and clinical factors …

Adiponectin, leptin, and resistin are dysregulated in patients infected by SARS-CoV-2

F Perrotta, F Scialò, M Mallardo, G Signoriello… - International Journal of …, 2023 - mdpi.com
Obesity, through adipose tissue (AT) inflammation and dysregulation, represents a critical
factor for COVID-19; here, we investigated whether serum levels of adiponectin, HMW …

[HTML][HTML] Course and survival of COVID-19 patients with comorbidities in relation to the trace element status at hospital admission

G Du Laing, M Petrovic, C Lachat, M De Boevre… - Nutrients, 2021 - mdpi.com
Selenium (Se) and zinc (Zn) are essential trace elements needed for appropriate immune
system responses, cell signalling and anti-viral defence. A cross-sectional observational …

COVID-19 and hypopituitarism

S Frara, P Loli, A Allora, C Santini, L di Filippo… - Reviews in Endocrine …, 2022 - Springer
Besides the pulmonary manifestations caused by severe acute respiratory syndrome
(SARS) coronavirus 2 (SARS-CoV-2), an emerging endocrine phenotype, which can heavily …

Hyperbaric oxygen therapy counters oxidative stress/inflammation-driven symptoms in long COVID-19 patients: preliminary outcomes

S Mrakic-Sposta, A Vezzoli, G Garetto, M Paganini… - Metabolites, 2023 - mdpi.com
Long COVID-19 patients show systemic inflammation and persistent symptoms such as
fatigue and malaise, profoundly affecting their quality of life. Since improving oxygenation …

Noncommunicable diseases, climate change and iniquities: What COVID‐19 has taught us about syndemic

A Di Ciaula, M Krawczyk, KJ Filipiak… - European Journal of …, 2021 - Wiley Online Library
Background COVID‐19 is generating clinical challenges, lifestyle changes, economic
consequences. The pandemic imposes to familiarize with concepts as prevention …