Lenvatinib for hepatocellular carcinoma: a literature review

T Hatanaka, A Naganuma, S Kakizaki - Pharmaceuticals, 2021 - mdpi.com
Lenvatinib, which is an oral multikinase inhibitor, showed non-inferiority to the sorafenib in
terms of overall survival (OS) and a higher objective response rate (ORR) and better …

Association between sarcopenia and prognosis of hepatocellular carcinoma: A systematic review and meta-analysis

C Jiang, Y Wang, W Fu, G Zhang, X Feng… - Frontiers in …, 2022 - frontiersin.org
Background Sarcopenia, characterized by the loss of muscle mass, strength, and physical
ability, occurs with aging and certain chronic illnesses such as chronic liver diseases and …

Association between sarcopenia and clinical outcomes in patients with hepatocellular carcinoma: an updated meta-analysis

Y Guo, Y Ren, L Zhu, L Yang, C Zheng - Scientific reports, 2023 - nature.com
Although numerous studies have reported the association between sarcopenia and the
prognosis of hepatocellular carcinoma (HCC) patients, there is lack of a newer and more …

Calf and arm circumference as simple markers for screening sarcopenia in patients with chronic liver disease

K Endo, T Sato, K Kakisaka… - Hepatology Research, 2021 - Wiley Online Library
Aim To prevent the progression of sarcopenia, early identification is important. We
investigated the usefulness of sarcopenia screening tests using the arm and calf …

Comparison of the prognostic effect of sarcopenia on atezolizumab plus bevacizumab and lenvatinib therapy in hepatocellular carcinoma patients

K Toshida, S Itoh, T Tomiyama, A Morinaga, Y Kosai… - Jgh …, 2022 - Wiley Online Library
Abstract Background and Aim Sarcopenia has received much attention as a poor prognostic
factor in various fields, and has also been reported to worsen prognosis in patients with …

Impact of sarcopenia and sarcopenic obesity on survival in patients with primary liver cancer: a systematic review and meta-analysis

X Li, X Huang, L Lei, S Tong - Frontiers in Nutrition, 2023 - frontiersin.org
Background Sarcopenia and sarcopenic obesity are associated with an increased possibility
of adverse clinical outcomes; however, the effects of sarcopenia and sarcopenic obesity on …

Relationship between accurate diagnosis of sarcopenia and prognosis in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab …

K Oura, A Morishita, T Manabe, K Takuma, M Nakahara… - Cancers, 2023 - mdpi.com
Simple Summary Although sarcopenia-related factors, including decreased skeletal muscle
index (SMI), have been reported to affect therapeutic efficacy and the occurrence of adverse …

The geriatric nutritional risk index predicts tolerability of lenvatinib in patients with hepatocellular carcinoma

A Kinoshita, N Hagiwara, A Osawa, T Akasu… - in vivo, 2022 - iv.iiarjournals.org
Background/Aim: We aimed to investigate the association between The Geriatric Nutritional
Risk Index (GNRI) and the tolerability of lenvatinib in patients with hepatocellular carcinoma …

Irisin in liver cirrhosis

M Kukla, L Skladany, T Menżyk, A Derra… - Journal of clinical …, 2020 - mdpi.com
Background: Sarcopenia is a prevalent muscle abnormality characterized by progressive
and generalized loss of skeletal muscle mass and strength, common among patients with …

[HTML][HTML] Nutritional status in patients with hepatocellular carcinoma: Potential relevance for clinical outcome

AM van Dijk, BJP Coppens, MA van Beers… - European Journal of …, 2022 - Elsevier
Background Impaired nutritional status is a risk factor for unfavorable outcome in cirrhosis.
Methods In this prospective cohort study in hepatocellular carcinoma patients referred for …