The Saccharomyces cerevisiae genome sequence, augmented by new data on gene
expression and function, continues to yield new findings about eukaryote genome evolution …

Understanding how chromatin is spatially and dynamically organized in the nucleus of
eukaryotic cells and how this affects genome functions is one of the main challenges of cell …

We study statistical properties of the Jensen-Shannon divergence D, which quantifies the
difference between probability distributions, and which has been widely applied to analyses …

We present a new computational approach to finding borders between coding and
noncoding DNA. This approach has two features:(i) DNA sequences are described by a 12 …

We elaborate on a unified thermodynamic description of multifractal distributions including
measures and functions. This new approach relies on the computation of partition functions …

We use the “wavelet transform microscope” to carry out a comparative statistical analysis of
DNA bending profiles and of the corresponding DNA texts. In the three kingdoms, one …

Using large amounts of long genomic sequences, we studied the compositional patterns of
eukaryotic genomes. We developed a simple measure, the compositional heterogeneity (or …

Large-scale statistical analysis of data sets associated with genome sequences plays an
important role in modern biology. A key component of such statistical analyses is the …

Here we present a study of statistical correlations among different positions in DNA
sequences and their implications by directly using the autocorrelation function. Such an …

Axiomatic design (AD) provides a framework to describe design objects and a set of axioms
to evaluate relations between intended functions and means by which they are achieved. It …