Cancer is driven by multiple types of genetic alterations, which range in size from point
mutations to whole-chromosome gains and losses, known as aneuploidy. Chromosome …

For several decades, multipotent mesenchymal stromal cells (MSCs) have been extensively
studied for their therapeutic potential across a wide range of diseases. In the preclinical …

Regenerative medicine is extensively interested in developing cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …

In addition to their stem/progenitor properties, mesenchymal stromal cells (MSCs) possess
broad immunoregulatory properties that are being investigated for potential clinical …

Both embryonic and adult stem cells are endowed with a superior capacity to prevent the
accumulation of genetic lesions, repair them, or avoid their propagation to daughter cells …

The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

Originally isolated from bone marrow, mesenchymal stromal cells (MSCs) have since been
obtained from various fetal and post-natal tissues and are the focus of an increasing number …

Research into mesenchymal stromal/stem cells (MSCs) has been particularly exciting in the
past five years. Our understanding of mechanisms of MSC-mediated tissue regeneration has …

Numerous clinical studies have shown a wide clinical potential of mesenchymal stromal
cells (MSCs) application. However, recent experience has accumulated numerous reports of …

Variability in induced pluripotent stem cell (iPSC) lines remains a concern for disease
modeling and regenerative medicine. We have used RNA-sequencing analysis and linear …